Literature DB >> 3622305

Cyclandelate in the treatment of vertigo of circulatory origin. A study in general practice.

F de Halleux.   

Abstract

A multicentre study with 622 patients has been undertaken to evaluate the efficacy of cyclandelate 1600 mg daily in the treatment of vertigo of circulatory origin in general practice. The characteristics of the patient population were consistent with the diagnosis of vertigo of circulatory origin. Patients with some risk factors, essentially a history of thrombosis and atherosclerotic patients, had more severe symptoms at the onset of the study. During the 3-month period of treatment with cyclandelate, the average global score of vertigo (0-10) decreased from 5.57 to 2.12 and the average scores of frequency, severity and duration of vertigo (0-4) decreased from 2.53, 2.55 and 2.26 to 0.98, 0.89 and 0.84, respectively. Patients previously treated with other anti-ischaemic drugs had similar responses compared to other patients. These results indicate that cyclandelate may be useful in the management of vertigo of circulatory origin in general practice.

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Year:  1987        PMID: 3622305     DOI: 10.2165/00003495-198700332-00021

Source DB:  PubMed          Journal:  Drugs        ISSN: 0012-6667            Impact factor:   9.546


  7 in total

1.  Clinical trial with cycladelate in otological disorders. (Preliminary observations).

Authors:  E M PULLEN; J R SURBER
Journal:  Curr Ther Res Clin Exp       Date:  1962-06

2.  [Flunarizine in patients with inadequate cerebral and peripheral circulation. Multicentric double blind study].

Authors:  K Domschky; M Nelson; B Dammhayn; E Terjung
Journal:  Med Welt       Date:  1977-06-10

3.  The effect of cyclandelate on cerebral circulation. A double blind trial with clinical and radiocirculographic investigations.

Authors:  O Eichhorn
Journal:  Vasc Dis       Date:  1965-11

Review 4.  [Therapeutic considerations on the subject of vascular disorders in otorhinolaryngology].

Authors:  W Cloetens; J Michel
Journal:  Acta Otorhinolaryngol Belg       Date:  1966

5.  Cyclandelate and a number of its metabolites inhibit discocyte-echinocyte transformations of human erythrocytes.

Authors:  W E Van den Hoven; D W Hall; J W Burns
Journal:  Br J Clin Pract Suppl       Date:  1984

6.  Inhibition of human platelet aggregation by cyclandelate.

Authors:  W E Van den Hoven; D W Hall
Journal:  Br J Clin Pract Suppl       Date:  1984

7.  Cyclandelate in the treatment of senile mental changes: a double-blind evaluation.

Authors:  D B Rao; E L Georgiev; P D Paul; A B Guzman
Journal:  J Am Geriatr Soc       Date:  1977-12       Impact factor: 5.562

  7 in total

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