Literature DB >> 36212603

Case Report and Literature Review of Giant Cutaneous Malignant Melanoma: What's Keeping Patients Away?

Jamie A Mawhinney1, Adrien Yvon1, Shahid Masood1.   

Abstract

Background. Giant cutaneous malignant melanoma (MM) is a term that has previously been used to define lesions that are at least 10 cm in diameter or 48 mm in thickness. Such tumours are rare. There is no substantial body of evidence considering why patients may delay presentation with MM until they reach this size. This case report presents one of the largest cases of giant cutaneous MM to date and the first in the literature to show excellent response to adjuvant immunotherapy. The patient was treated successfully and remains alive and well 12 months following initial surgery. A review of the literature discussing giant MM identified a significant need for education on the importance of seeking medical attention in order to prevent advanced disease, especially for vulnerable individuals.
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Entities:  

Keywords:  giant malignant melanoma; immunotherapy; malignant melanoma; oncology; reconstructive surgery

Year:  2022        PMID: 36212603      PMCID: PMC9516761     

Source DB:  PubMed          Journal:  Eplasty        ISSN: 1937-5719


  12 in total

1.  Giant melanoma displaying gross features reproducing parameters seen on dermoscopy.

Authors:  Vincenzo De Giorgi; Daniela Massi; Paolo Carli
Journal:  Dermatol Surg       Date:  2002-07       Impact factor: 3.398

2.  Giant primary melanoma with no apparent metastases: a report of 2 cases.

Authors:  Tracie Ann Chong; Lauren Strazzula; Mai P Hoang; Ryan Arakaki; Daniela Kroshinsky
Journal:  JAMA Dermatol       Date:  2014-05       Impact factor: 10.282

3.  A Case of Giant Primary Dermal Melanoma with BRAF V600E Mutation.

Authors:  Taichi Imamura; Yasuhiro Nakamura; Yukiko Teramoto; Sayuri Sato; Yuri Asami; Eiichi Arai; Akifumi Yamamoto
Journal:  Acta Derm Venereol       Date:  2016-08-23       Impact factor: 4.437

Review 4.  Giant melanoma of the abdomen: case report and revision of the published cases.

Authors:  Nicola di Meo; Giuseppe Stinco; Alessandro Gatti; Enzo Errichetti; Serena Bonin; Antonio Albano; Sara Trevisini; Giusto Trevisan
Journal:  Dermatol Online J       Date:  2014-07-15

5.  Giant melanoma: novel problem, same approach.

Authors:  Andre D Grisham
Journal:  South Med J       Date:  2010-11       Impact factor: 0.954

6.  Giant cutaneous melanomas: evidence for primary tumour induced dormancy in metastatic sites?

Authors:  William W Tseng; Judy A Doyle; Sheilagh Maguiness; Andrew E Horvai; Mohammed Kashani-Sabet; Stanley P L Leong
Journal:  BMJ Case Rep       Date:  2009-10-05

7.  Giant melanoma and depression.

Authors:  Javier del Boz; José Miguel García; Silvestre Martínez; Marina Gómez
Journal:  Am J Clin Dermatol       Date:  2009       Impact factor: 7.403

8.  Giant malignant melanoma: a case report.

Authors:  M V Kiyak; A K Yesilada; K Z Sevim; U Usta
Journal:  Acta Chir Plast       Date:  2012

Review 9.  Patient with giant upper limb melanoma presenting to a UK plastic surgery unit: differentials and experience of management.

Authors:  Calum Sinclair Honeyman; Paul Wilson
Journal:  BMJ Case Rep       Date:  2016-02-02

10.  Salvage surgery for a giant melanoma on the back.

Authors:  Schelto Kruijff; Robert Vink; Joost Klaase
Journal:  Rare Tumors       Date:  2011-07-11
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