Literature DB >> 36212247

PARATHYROID ADENOMA MIMICKING TUBERCULOSIS IN A PERITONEAL DIALYSIS PATIENT.

S Karahisar Şirali1, Ö Kavraz Tomar1, R Büberci1, A Z Bal1, M Duranay1.   

Abstract

The most common cause of hypercalcemia is parathyroid hyperplasia and carcinoma. Tuberculosis(TB) and sarcoidosis are the most common granulomatous diseases of the parathyroid. We report a case of parathyroid adenoma that can mimic many lesions. A 46-year-old woman on continuous ambulatory peritoneal dialysis (CAPD) with symptoms and signs of hypercalcemia. Laboratory findings were consistent with tertiary hyperparathyroidism. She underwent elective parathyroidectomy due to high PTH values despite effective treatment including calcimimetics and vitamin D receptor activators. Subtotal thyroidectomy and three and a half of parathyroid adenomas were removed. Histopathological examination revealed features of parathyroid adenoma with granulomatosis infection that supports tuberculosis. In order to confirm the pathological findings, the PCR study was performed on the pathology specimens. After obtaining a negative result, the treatment was stopped. We have reported a case of parathyroid adenoma that mimicking tuberculosis. ©2022 Acta Endocrinologica (Buc).

Entities:  

Keywords:  granulomatous inflammation; hyperparathyroidism; tuberculosis

Year:  2022        PMID: 36212247      PMCID: PMC9512386          DOI: 10.4183/aeb.2022.225

Source DB:  PubMed          Journal:  Acta Endocrinol (Buchar)        ISSN: 1841-0987            Impact factor:   1.104


  8 in total

1.  Parathyroid adenoma with necrotizing granulomatous inflammation presenting as primary hyperparathyroidism.

Authors:  P M Jacob; G C Sukumar; A Nair; S Thomas
Journal:  Endocr Pathol       Date:  2005       Impact factor: 3.943

Review 2.  Evaluation and management of primary hyperparathyroidism.

Authors:  S J Silverberg; J P Bilezikian
Journal:  J Clin Endocrinol Metab       Date:  1996-06       Impact factor: 5.958

Review 3.  Elevated parathyroid hormone levels after successful parathyroidectomy for primary hyperparathyroidism: a clinical review.

Authors:  Roberto de la Plaza Llamas; José Manuel Ramia Ángel; Vladimir Arteaga Peralta; Cristina García Amador; Aylhín Joana López Marcano; Aníbal Armando Medina Velasco; Begoña González Sierra; Alba Manuel Vázquez; Raquel Aránzazu Latorre Fragua
Journal:  Eur Arch Otorhinolaryngol       Date:  2017-12-05       Impact factor: 2.503

4.  Tuberculous granulomatous inflammation associated with adenoma of parathyroid gland manifesting as primary hyperparathyroidism.

Authors:  D K Kar; G Agarwal; B Mehta; J Agarwal; R K Gupta; T N Dhole; S K Mishra
Journal:  Endocr Pathol       Date:  2001       Impact factor: 3.943

5.  Parathyroid Adenoma Associated with Granulomatous Inflammation: A Curious Cause of Hypercalcaemia.

Authors:  Hena Paul Singh; Vikram Narang; Neena Sood; Harpreet Puri
Journal:  J Clin Diagn Res       Date:  2016-04-01

6.  Tuberculosis complicating tertiary hyperparathyroidism in a patient with end-stage renal disease: a case report.

Authors:  Hazim M Sadideen; Paul Blaker; Patrick O'Donnell; John Taylor; David J Goldsmith
Journal:  J Nephrol       Date:  2008 May-Jun       Impact factor: 3.902

7.  Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease.

Authors:  Martin Hewison; Fiona Burke; Katie N Evans; David A Lammas; David M Sansom; Philip Liu; Robert L Modlin; John S Adams
Journal:  J Steroid Biochem Mol Biol       Date:  2007-03       Impact factor: 4.292

8.  Granulomatous infiltration of a parathyroid adenoma presenting as primary hyperparathyroidism in a woman: a case report.

Authors:  Inan Anaforoğlu; Ciğdem Siviloğlu; Ayten Livaoğlu; Ekrem Algün
Journal:  J Med Case Rep       Date:  2010-12-09
  8 in total

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