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Literature DB >> 3620911

The neuronal growth-associated protein GAP-43 (B-50, F1): neuronal specificity, developmental regulation and regional distribution of the human and rat mRNAs.

R L Neve, N I Perrone-Bizzozero, S Finklestein, H Zwiers, E Bird, D M Kurnit, L I Benowitz.

Abstract

The protein that has been designated as GAP-43, B-50, F1 or pp46 is associated with the growth and modulation of neuronal connections. cDNA clones for the rat and human genes were isolated and used to demonstrate that the messenger RNA for the protein is expressed only in neurons, that its overall level is highest in the developing brain, and that in the adult human brain levels of the mRNA are highest in the associative neocortex.

Entities: Gene Species

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Year: 1987 PMID： 3620911 DOI： 10.1016/s0006-8993(87)80012-4

Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252

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Cited

24 in total

Review 1. Synaptic vesicle proteins and neuronal plasticity in adrenergic neurons.

Authors: X E Hou; A Dahlström
Journal: Neurochem Res Date: 2000-10 Impact factor: 3.996

Review 2. The role of protein kinase C and its neuronal substrates dephosphin, B-50, and MARCKS in neurotransmitter release.

Authors: P J Robinson
Journal: Mol Neurobiol Date: 1991 Impact factor: 5.590

Review 3. Molecular analysis of the function of the neuronal growth-associated protein GAP-43 by genetic intervention.

Authors: R L Neve; K J Ivins; L I Benowitz; M J During; A I Geller
Journal: Mol Neurobiol Date: 1991 Impact factor: 5.590

4. Coordinated expression of HuD and GAP-43 in hippocampal dentate granule cells during developmental and adult plasticity.

Authors: Federico Bolognani; Daniel C Tanner; Sayuri Nixon; Hirotaka J Okano; Hideyuki Okano; Nora I Perrone-Bizzozero
Journal: Neurochem Res Date: 2007-06-19 Impact factor: 3.996

The neuronal growth-associated protein GAP-43 (B-50, F1): neuronal specificity, developmental regulation and regional distribution of the human and rat mRNAs.

Review 1. Synaptic vesicle proteins and neuronal plasticity in adrenergic neurons.

Review 2. The role of protein kinase C and its neuronal substrates dephosphin, B-50, and MARCKS in neurotransmitter release.

Review 3. Molecular analysis of the function of the neuronal growth-associated protein GAP-43 by genetic intervention.

4. Coordinated expression of HuD and GAP-43 in hippocampal dentate granule cells during developmental and adult plasticity.

5. GAP-43 in the axons of mammalian CNS neurons regenerating into peripheral nerve grafts.

6. Immediate upstream promoter regions required for neurospecific expression of SNAP-25.

7. Post-transcriptional regulation of the GAP-43 gene by specific sequences in the 3' untranslated region of the mRNA.

8. Visual experience regulates gene expression in the developing striate cortex.

9. Growth-associated protein 43 is down-regulated in cultured astrocytes.

Review 10. Role of the growth-associated protein B-50/GAP-43 in neuronal plasticity.