Literature DB >> 36203295

Surgical Considerations to Improve Recovery in Acute Spinal Cord Injury.

Troy Q Tabarestani1, Nicholle E Lewis2, Margot Kelly-Hedrick1, Nina Zhang3, Brianna R Cellini3, Eric J Marrotte4, Theresa Williamson5,6, Haichen Wang7, Daniel T Laskowitz7, Timothy D Faw2,8, Muhammad M Abd-El-Barr9.   

Abstract

Acute traumatic spinal cord injury (SCI) can be a devastating and costly event for individuals, their families, and the health system as a whole. Prognosis is heavily dependent on the physical extent of the injury and the severity of neurological dysfunction. If not treated urgently, individuals can suffer exacerbated secondary injury cascades that may increase tissue injury and limit recovery. Initial recognition and rapid treatment of acute SCI are vital to limiting secondary injury, reducing morbidity, and providing the best chance of functional recovery. This article aims to review the pathophysiology of SCI and the most up-to-date management of the acute traumatic SCI, specifically examining the modern approaches to surgical treatments along with the ethical limitations of research in this field.

Entities:  

Keywords:  Ethics; Hemodynamics; Neurosurgery; Spinal cord injuries; Spinal injuries; Surgical decompression

Year:  2022        PMID: 36203295      PMCID: PMC9537855          DOI: 10.14245/ns.2244616.308

Source DB:  PubMed          Journal:  Neurospine        ISSN: 2586-6591


  153 in total

1.  Temporal-spatial pattern of acute neuronal and glial loss after spinal cord contusion.

Authors:  S D Grossman; L J Rosenberg; J R Wrathall
Journal:  Exp Neurol       Date:  2001-04       Impact factor: 5.330

2.  In vivo imaging of axonal degeneration and regeneration in the injured spinal cord.

Authors:  Martin Kerschensteiner; Martin E Schwab; Jeff W Lichtman; Thomas Misgeld
Journal:  Nat Med       Date:  2005-04-10       Impact factor: 53.440

3.  Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord.

Authors:  Kristina A Kigerl; John C Gensel; Daniel P Ankeny; Jessica K Alexander; Dustin J Donnelly; Phillip G Popovich
Journal:  J Neurosci       Date:  2009-10-28       Impact factor: 6.167

Review 4.  Management of thoracolumbar spine fractures.

Authors:  Kirkham B Wood; Weishi Li; Darren R Lebl; Darren S Lebl; Avraam Ploumis
Journal:  Spine J       Date:  2014-01       Impact factor: 4.166

5.  Exploring ethical conflicts in emergency trauma research: the COMBAT (Control of Major Bleeding after Trauma) study experience.

Authors:  Theresa L Chin; Ernest E Moore; Marilyn E Coors; James G Chandler; Arsen Ghasabyan; Jeffrey N Harr; John R Stringham; Christopher R Ramos; Sarah Ammons; Anirban Banerjee; Angela Sauaia
Journal:  Surgery       Date:  2014-10-14       Impact factor: 3.982

6.  Functional Outcomes in Individuals Undergoing Very Early (< 5 h) and Early (5-24 h) Surgical Decompression in Traumatic Cervical Spinal Cord Injury: Analysis of Neurological Improvement from the Austrian Spinal Cord Injury Study.

Authors:  Georg Mattiassich; Maria Gollwitzer; Franz Gaderer; Martina Blocher; Michael Osti; Markkus Lill; Reinhold Ortmaier; Thomas Haider; Wolfgang Hitzl; Herbert Resch; Stephanie Aschauer-Wallner
Journal:  J Neurotrauma       Date:  2017-08-10       Impact factor: 5.269

7.  Prominent oligodendrocyte genesis along the border of spinal contusion lesions.

Authors:  Richa Tripathi; Dana M McTigue
Journal:  Glia       Date:  2007-05       Impact factor: 7.452

8.  Lumbar Myeloid Cell Trafficking into Locomotor Networks after Thoracic Spinal Cord Injury.

Authors:  Christopher N Hansen; Diana M Norden; Timothy D Faw; Rochelle Deibert; Eric S Wohleb; John F Sheridan; Jonathan P Godbout; D Michele Basso
Journal:  Exp Neurol       Date:  2016-05-16       Impact factor: 5.330

9.  High-resolution intravital imaging reveals that blood-derived macrophages but not resident microglia facilitate secondary axonal dieback in traumatic spinal cord injury.

Authors:  Teresa A Evans; Deborah S Barkauskas; Jay T Myers; Elisabeth G Hare; Jing Qiang You; Richard M Ransohoff; Alex Y Huang; Jerry Silver
Journal:  Exp Neurol       Date:  2014-01-24       Impact factor: 5.330

Review 10.  Complete fracture-dislocation of the thoracolumbar spine without neurological deficit: A case report and review of the literature.

Authors:  Junfeng Zeng; Quan Gong; Hao Liu; Xin Rong; Chen Ding
Journal:  Medicine (Baltimore)       Date:  2018-03       Impact factor: 1.889

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