Literature DB >> 3620270

The effect of isoxicam on neutrophil and monocyte function.

J G Martinez, S I Murakami, M A Scheinberg.   

Abstract

1 Isoxicam was found to inhibit monocyte and neutrophil cell chemotaxis at therapeutic concentrations. 2 The effect was observed after in vitro incubation of normal cells and in vivo in patients with rheumatoid arthritis. 3 Compared to other NSAIDs studied in our laboratory, isoxicam was shown to have a broader spectrum of inhibitory action on the cells involved in the chronic inflammation associated with rheumatoid arthritis.

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Year:  1986        PMID： 3620270      PMCID： PMC1400968          DOI： 10.1111/j.1365-2125.1986.tb02991.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  4 in total

1.  Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.

Authors:  J R Vane
Journal:  Nat New Biol       Date:  1971-06-23

2.  The neutrophil in rheumatoid arthritis: its role and the inhibition of its activation by nonsteroidal antiinflammatory drugs.

Authors:  S Abramson; H Edelson; H Kaplan; W Given; G Weissmann
Journal:  Semin Arthritis Rheum       Date:  1983-08       Impact factor: 5.532

3.  The pathogenesis of rheumatoid arthritis and the immune response.

Authors:  M A Scheinberg
Journal:  Semin Arthritis Rheum       Date:  1983-08       Impact factor: 5.532

4.  The effect of piroxicam on neutrophil and monocyte-macrophage function.

Authors:  M A Scheinberg; H O Rueda; P C Matheus
Journal:  Eur J Rheumatol Inflamm       Date:  1983
  4 in total

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