| Literature DB >> 36198865 |
F Hoedeman1, P J Puiman2, E A L van den Heuvel3, M J Affourtit1, R Bakx4, M W Langendam5, E M van de Putte3, I M B Russel-Kampschoer3, M C M Schouten6, A H Teeuw7, H J de Koning8, H A Moll1.
Abstract
The objective of this study is to develop and validate a screening instrument for the recognition of child maltreatment in the emergency department (ED). Existing data on screening questions and outcomes (diagnosis of child maltreatment) from three large observational screening studies at eight different EDs in the Netherlands were harmonized. A multivariate logistic regression was performed to develop the Screening instrument for Child Abuse and Neglect (SCAN). The SCAN was validated by performing a cross-validation and calculating the discriminative ability. A total of 24,963 patients were included. Out of the potential screening questions the following questions were included in the final instrument: is the injury compatible with the history, and does it correspond to the child's developmental level? (aOR 10.40, 95% CI 5.69-19.02), was there an unnecessary delay in seeking medical help? (aOR 3.45, 95% CI 1.73-6.88) and is the behaviour/interaction of the child and parents (carers) appropriate? (aOR 14.67, 95% CI 7.93-27.13). The SCAN had a pooled AUC of 0.75 (95% CI 0.63-0.87) in the cross-validation. The question "Are there other signals that make you doubt the safety of the child and/or family?" (available in only one of the original datasets, OR 182.9; 95% CI 102.3-327.4) was by consensus added to the final SCAN.Entities:
Keywords: Checklist; Child maltreatment; Emergency medicine; Screening
Year: 2022 PMID: 36198865 PMCID: PMC9534589 DOI: 10.1007/s00431-022-04635-0
Source DB: PubMed Journal: Eur J Pediatr ISSN: 0340-6199 Impact factor: 3.860
Baseline characteristics of the included cases
| Characteristics | Dataset AMC | Dataset EMC | Dataset UMC | Total dataset |
|---|---|---|---|---|
| Gender | ||||
| Boy | 1753 (55.9) | 10,266 (56.5) | 2138 (58.3) | 14,157 (56.7) |
| Girl | 1383 (44.1) | 7893 (43.5) | 1530 (41.7) | 10,806 (43.3) |
| Age median (IQR) | 6.2 (2.4–11.6) | 3.3 (1.1–8.2) | 4.0 (2.5–5.5) | 3.8 (1.4–7.7) |
| < 4 years | 1154 (36.8) | 9985 (55.0) | 1821 (49.6) | 12,960 (51.9) |
| ≥ 4 to < 8 years | 628 (20.0) | 3522 (19.4) | 1847 (50.4) | 5997 (24.0) |
| ≥ 8 to < 12 years | 649 (20.7) | 2592 (14.3) | n.a | 3241 (13.0) |
| ≥ 12 to < 19 years | 705 (22.5) | 2060 (11.3) | n.a | 2765 (11.1) |
| Positive screening result before multiple imputation of screening questions* | ||||
| Yes | 267 (8.5) | 403 (2.2) | 121 (3.3) | 791 (3.2) |
| Positive screening result after multiple imputation of screening questions* | ||||
| Yes | 337 (10.7) | 407 (2.2) | 124 (3.4) | 868 (3.5) |
| Outcome measure A (consensus diagnosis) | ||||
| Yes | 41 (1.3) | 52 (0.3) | 9 (0.2) | 102 (0.4) |
| Outcome measure B (consensus diagnosis & reports Safe at Home centre for screened negatives) | ||||
| Yes | 90 (2.9) | 65 (0.4) | 54 (1.5) | 209 (0.8) |
n.a. not applicable
*See Table 2 for screening questions before multiple imputation, and Online Resource 5 for screening questions after multiple imputation
Screening questions
| Harmonized screening questions | Dataset AMC | Dataset EMC | Dataset UMC | Total dataset |
|---|---|---|---|---|
| Question 1: injury compatible with history and corresponding to child’s developmental level | ||||
| Yes | 2004 (63.9) | 17,039 (93.8) | 3606 (98.3) | 22,649 (90.7) |
| No* | 127 (4.0) | 79 (0.4) | 62 (1.7) | 268 (1.1) |
| Missing | 1005 (32.0) | 1041 (5.7) | 0 (0) | 2046 (8.2) |
| Question 2: unnecessary delay in seeking medical help | ||||
| Yes* | 77 (2.5) | 137 (0.8) | 40 (1.1) | 254 (1.0) |
| No | 2930 (93.4) | 17,952 (98.9) | 3628 (98.9) | 24,510 (98.2) |
| Missing | 129 (4.1) | 70 (0.4) | 0 (0) | 199 (0.8) |
| Question 3: consistent history | ||||
| Yes | n.a | 18,059 (99.4) | 3648 (99.5) | 21,707 (87.0) |
| No* | n.a | 78 (0.4) | 19 (0.5) | 97 (0.4) |
| Missing | 3136 (100) | 22 (0.1) | 1 (0.0) | 3159 (12.7) |
| Question 4: appropriate behaviour of the child, the parents and appropriate interaction | ||||
| Yes | 3076 (98.1) | 18,012 (99.2) | 3646 (99.4) | 24,734 (99.1) |
| No* | 60 (1.9) | 83 (0.5) | 21 (0.6) | 164 (0.7) |
| Missing | 0 (0) | 64 (0.4) | 1 (0.0) | 65 (0.3) |
| Question 5: physical injuries found with top-toe examination suspect for child maltreatment | ||||
| Yes* | 69 (2.2) | 52 (0.3) | 31 (0.8) | 152 (0.6) |
| No | 3067 (97.8) | 18,059 (99.4) | 3451 (94.1) | 24,577 (98.5) |
| Missing | 0 (0) | 48 (0.3) | 186 (5.1) | 234 (0.9) |
| Question 6: other signals that make you doubt the safety of child/family | ||||
| Yes* | n.a | 163 (0.9) | n.a | n.a |
| No | n.a | 17,878 (98.5) | n.a | n.a |
| Missing | n.a | 118 (0.6) | n.a | n.a |
n.a. not applicable
*positive answer on screening question = positive result. See Online Resource 5 for screening questions after multiple imputation
Complete and reduced adjusted model for the consensus diagnosis of child maltreatment (outcome measure A and B)
| aOR (95% CI) | aOR (95% CI) | ||||
|---|---|---|---|---|---|
| (Constant) | 0.005 (0.003–0.010) | 0.98 | 0.015 (0.010–0.021 | 0.000 | |
| Question 1 | Injury compatible with history and corresponding to child’s developmental level | 8.35 (4.33–16.11) | < 0.001 | 4.39 (2.54–7.60) | < 0.001 |
| Question 2 | Unnecessary delay in seeking medical help | 2.31 (1.07–5.00) | 0.03 | 1.71 (0.85–3.44) | 0.13 |
| Question 3 | Consistent history | 0.99 (0.30–3.26) | 0.99 | 1.61 (0.56–4.66) | 0.38 |
| Question 4 | Appropriate behaviour of the child, the parents and appropriate interaction | 6.91 (3.41–14.02) | < 0.001 | 5.27 (2.80–9.94) | < 0.001 |
| Question 5 | Physical injuries found with top-toe examination suspect for child maltreatment | 7.62 (3.69–15.75) | < 0.001 | 5.06 (2.66–9.63) | < 0.001 |
Models are adjusted for age, gender, hospital (n = 8) and the screening questions. Outcome measure A: unknown outcomes of screened negatives were analysed as a negative outcome. Outcome measure B: unknown outcomes for the negative-screened cases were supplemented based on the reports to the Safe at Home centre
Fig. 1Discriminative value (AUC with 95% confidence intervals) of the reduced model for the consensus diagnosis of child maltreatment for 3 internal–external cross-validations. Unknown outcomes of the screened negatives are analysed as negative outcome (outcome measure A)
Model performance subgroup analysis children < 5 years old compared to all children
| Outcome measure A | 0.79 (0.73–0.85) | 0.79 (0.71–0.86) |
| Outcome measure B | 0.64 (0.59–0.68) | 0.64 (0.58–0.69) |
| Outcome measure A | 0.75 (0.63–0.87) | 0.77 (0.62–0.93) |
| Outcome measure B | 0.61 (0.54–0.68) | 0.61 (0.51–0.71) |
Outcome measure A: unknown outcomes of screened negatives were analysed as negative outcome. Outcome measure B: unknown outcomes for the negative-screened cases were supplemented based on the reports to the Safe at Home centre
AUC area under the curve
Fig. 2Screening instrument for Child Abuse and Neglect (SCAN). *only regarding the patient delay, no doctors delay