Literature DB >> 36197419

MRSA outbreak in a Neonatal Intensive Care Unit in a developed country: importance of rapid detection of reservoirs and implementation of intervention measures.

Maria Luísa Moura1, Camila Fonseca Rizek2, Elisa Aguiar3, Ana Natiele da Silva Barros1, Sibeli Costa1, Sania Alves Dos Santos2, Ana Paula Marchi2, Maria Augusta Bento Cicaroni Gibelli4, Carla Regina Tragante4, Maria Rita Elmor de Araújo1, Flavia Rossi1, Thais Guimaraes1, Silvia Figueiredo Costa1,2.   

Abstract

We described a MRSA bloodstream infection outbreak that was rapidly identified and controlled in a Neonatal Intensive Care Unit after implementation of a bundle of measures, including PCR-screening and HCW decolonization. We found 35% of healthcare workers(HCW) colonized with S. aureus by PCR, one of them that presented skin lesion positive for MSSA (same clone and spa type than two patients). Our findings raise the hypothesis that the outbreak could be related to HCW colonization.

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Year:  2022        PMID: 36197419      PMCID: PMC9528307          DOI: 10.1590/S1678-9946202264058

Source DB:  PubMed          Journal:  Rev Inst Med Trop Sao Paulo        ISSN: 0036-4665            Impact factor:   2.169


  17 in total

1.  Molecular epidemiology of methicillin resistant Staphylococcus aureus isolated from newborns in a hospital in Rio de Janeiro, Brazil.

Authors:  M M Loureiro; B A de Moraes; M R Quadra; G S Pinheiro; P N Suffys; M D Asensi
Journal:  Mem Inst Oswaldo Cruz       Date:  2000 Nov-Dec       Impact factor: 2.743

Review 2.  Epidemiology and diagnosis of health care-associated infections in the NICU.

Authors:  Richard A Polin; Susan Denson; Michael T Brady
Journal:  Pediatrics       Date:  2012-03-26       Impact factor: 7.124

3.  CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting.

Authors:  Teresa C Horan; Mary Andrus; Margaret A Dudeck
Journal:  Am J Infect Control       Date:  2008-06       Impact factor: 2.918

4.  Spread of methicillin-resistant Staphylococcus aureus in a neonatal intensive unit associated with understaffing, overcrowding and mixing of patients.

Authors:  B M Andersen; R Lindemann; K Bergh; B-I Nesheim; G Syversen; N Solheim; F Laugerud
Journal:  J Hosp Infect       Date:  2002-01       Impact factor: 3.926

5.  Outbreak among healthy newborns due to a new variant of USA300-related meticillin-resistant Staphylococcus aureus.

Authors:  H Lee; E S Kim; C Choi; H Seo; M Shin; J H Bok; J E Cho; C J Kim; J W Shin; T S Kim; K H Song; K U Park; B I Kim; H B Kim
Journal:  J Hosp Infect       Date:  2014-04-30       Impact factor: 3.926

6.  Virulence and resistance profiles of MRSA isolates in pre- and post-liver transplantation patients using microarray.

Authors:  Inneke Marie van der Heijden; Larissa Marques de Oliveira; Glauber Costa Brito; Edson Abdala; Maristela Pinheiro Freire; Flavia Rossi; Luiz Augusto Carneiro D'Albuquerque; Anna Sara Shafferman Levin; Silvia Figueiredo Costa
Journal:  J Med Microbiol       Date:  2016-07-29       Impact factor: 2.472

7.  Transmission of Staphylococcus aureus from maternity unit staff members to newborns disclosed through spa typing.

Authors:  Andreas Matussek; Jan Taipalensuu; Ing-Marie Einemo; Malena Tiefenthal; Sture Löfgren
Journal:  Am J Infect Control       Date:  2007-03       Impact factor: 2.918

8.  An outbreak of methicillin-resistant Staphylococcus aureus in a neonatal intensive care unit.

Authors:  Lisa Saiman; Alicia Cronquist; Fann Wu; Juyan Zhou; David Rubenstein; William Eisner; Barry N Kreiswirth; Phyllis Della-Latta
Journal:  Infect Control Hosp Epidemiol       Date:  2003-05       Impact factor: 3.254

9.  Rapid determination of hospital-acquired meticillin-resistant Staphylococcus aureus lineages.

Authors:  Joshua D Cockfield; Smriti Pathak; Jonathan D Edgeworth; Jodi A Lindsay
Journal:  J Med Microbiol       Date:  2007-05       Impact factor: 2.472

10.  Characterization of the clonal profile of MRSA isolated in neonatal and pediatric intensive care units of a University Hospital.

Authors:  Valéria Cataneli Pereira; Danilo Flávio Moraes Riboli; Maria de Lourdes Ribeiro de Souza da Cunha
Journal:  Ann Clin Microbiol Antimicrob       Date:  2014-11-07       Impact factor: 3.944

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