| Literature DB >> 3619635 |
Abstract
A single dose of clofibrate (400 mg/kg), given to rats, increased the incorporation of (3H)thymidine into liver DNA, in a period of 20-30 h after administration. However, (3H)thymidine incorporation into hepatic DNA of rats treated repeatedly was identical to that of control animals. After the administration of a single dose of clofibrate a small increase in (3H)thymidine incorporation also occurred in kidney DNA; repeated doses, however, resulted in a marked suppression of labeling.Entities:
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Year: 1987 PMID： 3619635 DOI： 10.1007/bf00296965
Source DB: PubMed Journal: Arch Toxicol ISSN： 0340-5761 Impact factor: 5.153