Literature DB >> 3619431

Erythromycin bioactivity is stable in ophthalmic ointment used for prophylaxis of neonatal gonococcal conjunctivitis.

M G Bialer, E J Baron, R G Harper.   

Abstract

Erythromycin ophthalmic ointment (E. Fougera & Co., Melville, N.Y.) and erythromycin gluceptate standards prepared in ointment base were stored at room temperature and heated at temperatures up to 45 degrees C for as long as 6 h before being assayed for bioactivity. We were unable to detect any significant loss of antibiotic bioactivity.

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Year:  1987        PMID: 3619431      PMCID: PMC284221          DOI: 10.1128/AAC.31.6.954

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  17 in total

Review 1.  Ophthalmia neonatorum due to neisseria gonorrhoeae: prevention and treatment.

Authors:  R Rothenberg
Journal:  Sex Transm Dis       Date:  1979 Apr-Jun       Impact factor: 2.830

2.  An evaluation of the stability of buffered erythromycin ointments.

Authors:  H SHEINAUS; C O LEE
Journal:  J Am Pharm Assoc Am Pharm Assoc       Date:  1955-01

3.  Microbiological diffusion assay II: design and applications.

Authors:  F Kavanagh
Journal:  J Pharm Sci       Date:  1975-07       Impact factor: 3.534

4.  Sheabutter V: effect of particle size on release of medicament from ointment.

Authors:  G H Konning; H C Mital
Journal:  J Pharm Sci       Date:  1978-03       Impact factor: 3.534

5.  Ophthalmic ointments.

Authors:  J S Robin; P P Ellis
Journal:  Surv Ophthalmol       Date:  1978 Mar-Apr       Impact factor: 6.048

6.  [Stability of efficacy of commercially available antibiotic eye ointments].

Authors:  K Mishima; S Kakimoto; S Nakamura
Journal:  Nihon Ganka Kiyo       Date:  1965-01

Review 7.  Prophylaxis of neonatal conjunctivitis. An analytic review.

Authors:  G A Bernstein; J P Davis; M L Katcher
Journal:  Clin Pediatr (Phila)       Date:  1982-09       Impact factor: 1.168

8.  Non-gonococcal ophthalmitis associated with erythromycin ointment prophylaxis of gonococcal ophthalmia neonatorum.

Authors:  B R Mooney; J A Green; B J Epstein; P A Hashisaki
Journal:  Infect Control       Date:  1984-03

9.  Erythromycin ointment for ocular prophylaxis of neonatal chlamydial infection.

Authors:  M R Hammerschlag; J W Chandler; E R Alexander; M English; W T Chiang; L Koutsky; D A Eschenbach; J R Smith
Journal:  JAMA       Date:  1980-11-21       Impact factor: 56.272

10.  Gonococcal conjunctivitis in a four-month-old infant.

Authors:  B Fivush; C L Woodward; E R Wald
Journal:  Sex Transm Dis       Date:  1980 Jan-Mar       Impact factor: 2.830

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