Literature DB >> 36187579

Intrathoracic Extension of a Giant Cell Tumour of the Medial End of Clavicle: A Case Report with Review of Literature.

Shaswat Mishra1, Manish Jain1, Sandeep Gavhale1, Sagar Bansal1, Sanjeev Ghildiyal1, Mitali Mokashi1.   

Abstract

Introduction: The clavicle is a very rare site for primary bone tumours, and Giant cell tumours of the clavicle are even rarer. Very few cases have been reported in the literature. Method: The authors report a rare presentation of intrathoracic extension of a giant cell tumour of the medial end of the clavicle, in an 18-year-old female. The patient had painful swelling at the sternal end of the clavicle associated with a painful shoulder range of motion. Complete resection of the mass was done, preserving the lateral half of the clavicle. Result and Discussion: At a 3-year follow-up, the patient has a good clinical outcome with no signs of recurrence. Being a very rare entity, no clear guidelines are available for the management of GCT of Clavicle. Adequate resection of the tumour mass remains the mainstay of treatment and has shown promising results. Denosumab has been proved to be effective in some studies, but the high cost of treatment is a major limitation in the Indian scenario.
Conclusion: Resection of the tumour mass with partial cleidectomy provided good results in this patient. © Indian Orthopaedics Association 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Entities:  

Keywords:  Benign tumours; Clavicle; Giant Cell Tumour; Intrathoracic extension; Locally aggressive; Medial-end clavicle; Partial cleidectomy

Year:  2022        PMID: 36187579      PMCID: PMC9485364          DOI: 10.1007/s43465-022-00726-0

Source DB:  PubMed          Journal:  Indian J Orthop        ISSN: 0019-5413            Impact factor:   1.033


  18 in total

Review 1.  From the archives of AFIP. Imaging of giant cell tumor and giant cell reparative granuloma of bone: radiologic-pathologic correlation.

Authors:  M D Murphey; G C Nomikos; D J Flemming; F H Gannon; H T Temple; M J Kransdorf
Journal:  Radiographics       Date:  2001 Sep-Oct       Impact factor: 5.333

Review 2.  Giant cell tumour occurring in the clavicle: a report of two cases.

Authors:  B Friedman; J Nerubay; F Lokiec; H Horoszowski; A Yelin
Journal:  Respir Med       Date:  1989-03       Impact factor: 3.415

3.  A case of giant-cell tumor of the clavicle.

Authors:  M H Beg; M M Ansari; R Uddin; M Naim
Journal:  Acta Orthop Scand       Date:  1989-02

4.  Osteoid osteoma of the clavicle.

Authors:  M J Klein; R Lusskin; M H Becker; S C Antopol
Journal:  Clin Orthop Relat Res       Date:  1979-09       Impact factor: 4.176

Review 5.  The current standing on the use of denosumab in giant cell tumour of the bone.

Authors:  Vivek Ajit Singh; Ajay Puri
Journal:  J Orthop Surg (Hong Kong)       Date:  2020 Sep-Dec       Impact factor: 1.118

6.  Denosumab May Increase the Risk of Local Recurrence in Patients with Giant-Cell Tumor of Bone Treated with Curettage.

Authors:  Costantino Errani; Shinji Tsukamoto; Giulio Leone; Alberto Righi; Manabu Akahane; Yasuhito Tanaka; Davide Maria Donati
Journal:  J Bone Joint Surg Am       Date:  2018-03-21       Impact factor: 5.284

7.  Giant-cell tumor of bone.

Authors:  M Campanacci; N Baldini; S Boriani; A Sudanese
Journal:  J Bone Joint Surg Am       Date:  1987-01       Impact factor: 5.284

8.  Giant cell tumor of the clavicle: report of a case in a rare location with consideration of surgical method.

Authors:  Satoshi Nagano; Toru Tsuchimochi; Masahiro Yokouchi; Takao Setoguchi; Hiromi Sasaki; Hirofumi Shimada; Shunsuke Nakamura; Yasuhiro Ishidou; Takuya Yamamoto; Setsuro Komiya
Journal:  BMC Musculoskelet Disord       Date:  2015-06-12       Impact factor: 2.362

9.  Giant cell tumour of clavicle: Occurrence of a common tumour in a rare location.

Authors:  Kavin Khatri; Jagdeep Singh; Anoop Kalia; Anshul Dahuja
Journal:  Int J Surg Case Rep       Date:  2016-10-25

10.  Rare presentation of giant cell tumor of bone in the lateral end of the clavicle.

Authors:  Jeetendra Bajpai; Sumit Saini; Akansha Bajpai; Ruchit Khera
Journal:  Am J Case Rep       Date:  2013-07-05
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