Literature DB >> 3618708

Assessment of visual impairment in patients with Alzheimer's disease.

A A Sadun, M Borchert, E DeVita, D R Hinton, C J Bassi.   

Abstract

We examined five patients with Alzheimer's disease who complained of poor vision. Two patients had mild Alzheimer's disease; they complained of problems with reading and of "bumping into things," yet both had normal visual acuities. One patient with moderate Alzheimer's disease had abnormal eye movements, visual-evoked potentials, and contrast sensitivity. The other two patients had severe Alzheimer's disease. Despite difficulties in performing the examination, we were able to see moderate impairments in visual acuity and visual fields, as well as marked dyschromatopsia, severe deficits in contrast sensitivity, and markedly abnormal eye movements and visual-evoked potentials.

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Year:  1987        PMID: 3618708     DOI: 10.1016/0002-9394(87)90001-8

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN: 0002-9394            Impact factor:   5.258


  62 in total

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2.  Categorization of object descriptions in Alzheimer's disease and frontotemporal dementia: limitation in rule-based processing.

Authors:  Murray Grossman; Edward E Smith; Phyllis L Koenig; Guila Glosser; Jina Rhee; Kari Dennis
Journal:  Cogn Affect Behav Neurosci       Date:  2003-06       Impact factor: 3.282

3.  Ocular changes in TgF344-AD rat model of Alzheimer's disease.

Authors:  Yuchun Tsai; Bin Lu; Alexander V Ljubimov; Sergey Girman; Fred N Ross-Cisneros; Alfredo A Sadun; Clive N Svendsen; Robert M Cohen; Shaomei Wang
Journal:  Invest Ophthalmol Vis Sci       Date:  2014-01-29       Impact factor: 4.799

4.  Assessing vision in patients with Alzheimer's disease.

Authors:  A A Sadun
Journal:  West J Med       Date:  1988-06

Review 5.  Paradigm Shifts in Ophthalmic Diagnostics.

Authors:  J Sebag; Alfredo A Sadun; Eric A Pierce
Journal:  Trans Am Ophthalmol Soc       Date:  2016-08

6.  Myelinated axon number in the optic nerve is unaffected by Alzheimer's disease.

Authors:  D C Davies; P McCoubrie; B McDonald; K A Jobst
Journal:  Br J Ophthalmol       Date:  1995-06       Impact factor: 4.638

7.  Energy metabolism of the visual system.

Authors:  Margaret T T Wong-Riley
Journal:  Eye Brain       Date:  2010-07-22

8.  Amyloid-beta deposits lead to retinal degeneration in a mouse model of Alzheimer disease.

Authors:  Allison Ning; Jing Cui; Eleanor To; Karen Hsiao Ashe; Joanne Matsubara
Journal:  Invest Ophthalmol Vis Sci       Date:  2008-06-19       Impact factor: 4.799

9.  Amyloid-peptide vaccinations reduce {beta}-amyloid plaques but exacerbate vascular deposition and inflammation in the retina of Alzheimer's transgenic mice.

Authors:  Bingqian Liu; Suhail Rasool; Zhikuan Yang; Charles G Glabe; Steven S Schreiber; Jian Ge; Zhiqun Tan
Journal:  Am J Pathol       Date:  2009-10-15       Impact factor: 4.307

10.  Relationship of measures of frailty to visual function: the Beaver Dam Eye Study.

Authors:  Barbara E K Klein; Ronald Klein; Michael D Knudtson; Kristine E Lee
Journal:  Trans Am Ophthalmol Soc       Date:  2003
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