Literature DB >> 3618463

A method for the continuous measurement of respiration and vapor uptake in rats.

A R Dahl, T P Gugliotta, R L Hanson, J L Mauderly, S J Rothenberg.   

Abstract

A method for determining the uptake of inhaled vapors in rats is described. The method uses gas chromatographic data to enable calculations of vapor concentration differences upstream and downstream from a rat exposed to the vapor by the nose-only route. Respiratory data are recorded simultaneously. The data can be used to determine the rate of uptake, uptake as a fraction of vapor inhaled and the effects of vapor inhalation on respiration.

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Year:  1987        PMID: 3618463     DOI: 10.1080/15298668791385129

Source DB:  PubMed          Journal:  Am Ind Hyg Assoc J        ISSN: 0002-8894


  1 in total

1.  Species differences in the metabolism and disposition of inhaled 1,3-butadiene and isoprene.

Authors:  A R Dahl; W E Bechtold; J A Bond; R F Henderson; J L Mauderly; B A Muggenburg; J D Sun; L S Birnbaum
Journal:  Environ Health Perspect       Date:  1990-06       Impact factor: 9.031

  1 in total

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