Literature DB >> 3618129

Olfactory bulb changes in Alzheimer's disease.

T G Ohm, H Braak.   

Abstract

Olfactory bulbs in cases of Alzheimer's disease and age-matched controls have been examined by means of combining silver staining of pathological filaments with pigment-Nissl staining of the cell bodies. Neuritic plaques were found in the anterior olfactory nucleus. Neurofibrillary tangles and neuropil threads occurred in the anterior olfactory nucleus and in all layers of the olfactory bulb except the outer fibrous layer. The tangle-bearing neurons of the olfactory bulb were identified as tufted cells, outer granule cells, and two different types of nerve cells forming the rostral part of the anterior olfactory nucleus.

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Year:  1987        PMID: 3618129     DOI: 10.1007/bf00688261

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN: 0001-6322            Impact factor:   17.088


  12 in total

1.  Alzheimer's neurofibrillary changes. A topographic study.

Authors:  A HIRANO; H M ZIMMERMAN
Journal:  Arch Neurol       Date:  1962-09

2.  The histology of the human olfactory bulb and the extracerebral part of the tract; a study with silver-carbonate.

Authors:  L LISS
Journal:  Ann Otol Rhinol Laryngol       Date:  1956-09       Impact factor: 1.547

3.  Clinical observations of impaired cranial nerve function in senile dementia.

Authors:  S Waldton
Journal:  Acta Psychiatr Scand       Date:  1974       Impact factor: 6.392

4.  Two new lesions in Alzheimer's disease.

Authors:  P Averback
Journal:  Lancet       Date:  1983-11-19       Impact factor: 79.321

5.  Olfactory tubercle choline acetyltransferase activity in Alzheimer-type dementia, Down's syndrome and Huntington's chorea.

Authors:  J Simpson; C M Yates; A Gordon; D M St Clair
Journal:  J Neurol Neurosurg Psychiatry       Date:  1984-10       Impact factor: 10.154

6.  The olfactory bulbs in Alzheimer's disease.

Authors:  M M Esiri; G K Wilcock
Journal:  J Neurol Neurosurg Psychiatry       Date:  1984-01       Impact factor: 10.154

7.  Olfactory dysfunction in Alzheimer's disease and Parkinson's disease.

Authors:  M Serby; J Corwin; P Conrad; J Rotrosen
Journal:  Am J Psychiatry       Date:  1985-06       Impact factor: 18.112

8.  Olfaction in dementia.

Authors:  M Serby; J Corwin; A Novatt; P Conrad; J Rotrosen
Journal:  J Neurol Neurosurg Psychiatry       Date:  1985-08       Impact factor: 10.154

9.  Plaques, tangles and dementia. A quantitative study.

Authors:  G K Wilcock; M M Esiri
Journal:  J Neurol Sci       Date:  1982-11       Impact factor: 3.181

10.  The limbic system in Alzheimer's disease. A neuropathologic investigation.

Authors:  M W Hopper; F S Vogel
Journal:  Am J Pathol       Date:  1976-10       Impact factor: 4.307

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  39 in total

1.  Olfactory ERPs in an odor/visual congruency task differentiate ApoE ε4 carriers from non-carriers.

Authors:  Joel Kowalewski; Claire Murphy
Journal:  Brain Res       Date:  2011-12-20       Impact factor: 3.252

2.  Disruption of odour quality coding in piriform cortex mediates olfactory deficits in Alzheimer's disease.

Authors:  Wen Li; James D Howard; Jay A Gottfried
Journal:  Brain       Date:  2010-08-19       Impact factor: 13.501

3.  Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis.

Authors:  Beate Winner; Edward Rockenstein; D Chichung Lie; Robert Aigner; Michael Mante; Ulrich Bogdahn; Sebastien Couillard-Despres; Eliezer Masliah; Jürgen Winkler
Journal:  Neurobiol Aging       Date:  2007-01-31       Impact factor: 4.673

4.  Odorant Item Specific Olfactory Identification Deficit May Differentiate Alzheimer Disease From Aging.

Authors:  Matthew R Woodward; Muhammad Ubaid Hafeez; Qianya Qi; Ahmed Riaz; Ralph H B Benedict; Li Yan; Kinga Szigeti
Journal:  Am J Geriatr Psychiatry       Date:  2018-04-19       Impact factor: 4.105

5.  Heat shock protein responses to aging and proteotoxicity in the olfactory bulb.

Authors:  Tyler S Crum; Amanda M Gleixner; Jessica M Posimo; Daniel M Mason; Matthew T Broeren; Scott D Heinemann; Peter Wipf; Jeffrey L Brodsky; Rehana K Leak
Journal:  J Neurochem       Date:  2015-03-05       Impact factor: 5.372

6.  Somatostatin-14-like immunoreactive neurons and fibres in the human olfactory bulb.

Authors:  T G Ohm; E Braak; A Probst
Journal:  Anat Embryol (Berl)       Date:  1988

7.  Validation of olfactory deficit as a biomarker of Alzheimer disease.

Authors:  Matthew R Woodward; Chaitanya V Amrutkar; Harshit C Shah; Ralph H B Benedict; Sanjanaa Rajakrishnan; Rachelle S Doody; Li Yan; Kinga Szigeti
Journal:  Neurol Clin Pract       Date:  2017-02

Review 8.  The role of the amyloid protein precursor (APP) in Alzheimer's disease: does the normal function of APP explain the topography of neurodegeneration?

Authors:  D H Small
Journal:  Neurochem Res       Date:  1998-05       Impact factor: 3.996

9.  Olfactory Dysfunction in the Elderly: Basic Circuitry and Alterations with Normal Aging and Alzheimer's Disease.

Authors:  Arjun V Masurkar; D P Devanand
Journal:  Curr Geriatr Rep       Date:  2014-06-01

10.  Immunodetection of the amyloid P component in Alzheimer's disease.

Authors:  T Duong; E C Pommier; A B Scheibel
Journal:  Acta Neuropathol       Date:  1989       Impact factor: 17.088

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