| Literature DB >> 36175812 |
Ariel Kenig1,2, Yonatan Oster2,3, Ronit Cohen-Poradosu4, Klaris Reisenberg5, Anat Wieder-Finesod6,7, Mirit Hershman-Sarafov8, Ilana Oren9, Gabriel Weber10,11, Ron Dagan12, Gili Regev-Yochay7,13, Jacob Strahilevitz14,15.
Abstract
In order to characterize pneumococcal endovascular infection in the post-vaccination era, a retrospective nationwide study based on the Israeli Adult IPD database was conducted. Between 2010 and 2019, 0.6% (23 cases) of IPD cases were of endovascular type, occurring mainly in males (72.3%) with underlying medical conditions (78.2%). Additional pneumococcal source (10 patients) and concomitant infections were not uncommon. Penicillin and ceftriaxone susceptibility rates were 65.2% and 91.3%, respectively; 60.9% of the isolates were not covered by the pneumococcal conjugate vaccine. 21.7% of patients died during hospitalization. In conclusion, pneumococcal endovascular infections still carry significant morbidity and mortality.Entities:
Keywords: Endovascular infections; Infective endocarditis; Invasive pneumococcal disease; Streptococcus pneumoniae
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Year: 2022 PMID： 36175812 DOI： 10.1007/s10096-022-04500-w
Source DB: PubMed Journal: Eur J Clin Microbiol Infect Dis ISSN： 0934-9723 Impact factor: 5.103