| Literature DB >> 3617467 |
Abstract
The blood level and the basic pharmacokinetic parameters (kel, Cop, T 1/2, AUC) of amoxicillin trihydrate were studied following its oral application to albino rats with experimentally injured kidneys (potassium chromate) and liver (tetrachloromethane). It was found that the impairment of these organs changed the extent of absorption, distribution, and excretion of the antibiotic.Entities:
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Year: 1987 PMID： 3617467
Source DB: PubMed Journal: Vet Med Nauki ISSN： 0324-1068