Literature DB >> 36171310

Innovative chemistry yields potential antidepressant drugs.

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Abstract

Entities:  

Keywords:  Chemical biology; Drug discovery; Neuroscience

Year:  2022        PMID： 36171310     DOI： 10.1038/d41586-022-03020-z

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   69.504


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  5 in total

1.  Crystal Structure of an LSD-Bound Human Serotonin Receptor.

Authors:  Daniel Wacker; Sheng Wang; John D McCorvy; Robin M Betz; A J Venkatakrishnan; Anat Levit; Katherine Lansu; Zachary L Schools; Tao Che; David E Nichols; Brian K Shoichet; Ron O Dror; Bryan L Roth
Journal:  Cell       Date:  2017-01-26       Impact factor: 41.582

2.  Highly diastereoselective synthesis of tetrahydropyridines by a C-H activation-cyclization-reduction cascade.

Authors:  Simon Duttwyler; Colin Lu; Arnold L Rheingold; Robert G Bergman; Jonathan A Ellman
Journal:  J Am Chem Soc       Date:  2012-02-22       Impact factor: 15.419

Review 3.  The promises and perils of psychedelic pharmacology for psychiatry.

Authors:  Tristan D McClure-Begley; Bryan L Roth
Journal:  Nat Rev Drug Discov       Date:  2022-03-17       Impact factor: 84.694

4.  Synthon-based ligand discovery in virtual libraries of over 11 billion compounds.

Authors:  Arman A Sadybekov; Anastasiia V Sadybekov; Yongfeng Liu; Christos Iliopoulos-Tsoutsouvas; Xi-Ping Huang; Julie Pickett; Blake Houser; Nilkanth Patel; Ngan K Tran; Fei Tong; Nikolai Zvonok; Manish K Jain; Olena Savych; Dmytro S Radchenko; Spyros P Nikas; Nicos A Petasis; Yurii S Moroz; Bryan L Roth; Alexandros Makriyannis; Vsevolod Katritch
Journal:  Nature       Date:  2021-12-15       Impact factor: 69.504

5.  Ultra-large library docking for discovering new chemotypes.

Authors:  Jiankun Lyu; Sheng Wang; Trent E Balius; Isha Singh; Anat Levit; Yurii S Moroz; Matthew J O'Meara; Tao Che; Enkhjargal Algaa; Kateryna Tolmachova; Andrey A Tolmachev; Brian K Shoichet; Bryan L Roth; John J Irwin
Journal:  Nature       Date:  2019-02-06       Impact factor: 49.962
  5 in total

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