| Literature DB >> 36161859 |
Ryan T Duong1, Omar Elghawy1, Amen B Nigussie1, Joseph D Bogaard2, James T Patrie3, Yevgeniy Eugene Shildkrot4.
Abstract
OBJECTIVE: To examine outcomes of different surgical modalities for correcting primary rhegmatogenous retinal detachments in patients younger than 50 years of age. METHODS AND ANALYSIS: A single-centre, retrospective, cohort study of 754 patients who underwent retinal surgery at the University of Virginia Hospital between 1 July 2012 and 1 July 2020 was conducted. Exclusion criteria were patients less than 18 or over 50 years of age, repeat detachments, second eyes of patients with bilateral detachments and follow-up less than 3 months. A multivariate regression model was used to compare overall outcomes in patients.Entities:
Keywords: retina; treatment surgery; vision; vitreous
Mesh:
Year: 2022 PMID: 36161859 PMCID: PMC9289014 DOI: 10.1136/bmjophth-2021-000894
Source DB: PubMed Journal: BMJ Open Ophthalmol ISSN: 2397-3269
Figure 1Flow sheet demonstrating number of patients excluded by each exclusion criterion. RRD, rhegmatogenous retinal detachment; UVA, University of Virginia.
Patient demographic information, ocular history and detachment characterstics
| Overall | Vitrectomy | Scleral buckle | Pneumatic retinopexy | Combined scleral buckle and vitrectomy (n=13) | ||
| Demographics | Male | 53 (61.6%) | 30 (78.9%) | 12 (54.5%) | 4 (30.8%) | 7 (53.0%) |
| Female | 33 (38.4%) | 8 (21.1%) | 10 (45.5%) | 9 (69.2%) | 6 (46.2%) | |
| Mean age | 36.5±9.7 | 38.4±9.6 | 31.1±8.2 | 38.4±10.7 | 36.8±9.7 | |
| Age 18–29 | 23 (26.7%) | 7 (18.4%) | 8 (36.4%) | 3 (23.1%) | 5 (38.5%) | |
| Age 30–39 | 25 (29.1%) | 11 (28.9%) | 10 (45.5%) | 3 (23.1%) | 1 (7.6%) | |
| Age 40–50 | 38 (44.2%) | 20 (52.6%) | 4 (18.2%) | 7 (53.8%) | 7 (53.8%) | |
| Patient history | Prior vitrectomy | 3 (3.49%) | 2 (5.26%) | 0 (0%) | 0 (0%) | 1 (7.69%) |
| Prior glaucoma surgery | 3 (3.49%) | 2 (5.26%) | 0 (0%) | 0 (0%) | 1 (7.69%) | |
| Prior cataract surgery* | 21 (23.2%) | 13 (34.2%) | 1 (4.54%) | 2 (15.4%) | 5 (35.7%) | |
| Uveitis | 7 (8.14%) | 5 (13.2%) | 0 (0%) | 2 (15.4%) | 0 (0%) | |
| Prior ocular injury | 7 (8.14%) | 5 (13.9%) | 1 (4.54%) | 0 (0%) | 1 (7.69%) | |
| Macular oedema | 4 (4.65%) | 4 (10.5%) | 0 (0 %) | 0 (0%) | 0 (0 %) | |
| Glaucoma | 10 (11.6%) | 5 (13.2%) | 2 (9.09%) | 1 (7.69%) | 2 (15.4%) | |
| Detachment characteristics | Multiple tears* | 21 (24.4%) | 4 (11.0%) | 7 (31.8%) | 4 (33.3%) | 6 (46.2%) |
| Macular involvement* | 54 (62.8%) | 26 (68.4%) | 13 (59.1%) | 4 (30.8%) | 11 (84.6%) | |
| Giant tear | 7 (8.14%) | 5 (13.2%) | 0 (0%) | 0 (0%) | 2 (15.4%) | |
| 1–3 clock hour involved | 36 (58.1%) | 11 (40.7%) | 10 (66.7%) | 6 (60.0%) | 9 (90.0%) | |
| 4–7 clock hours involved | 22 (35.5%) | 14 (51.9%) | 4 (26.7%) | 3 (30.0%) | 1 (10.0%) | |
| ≥8 clock hours involved | 4 (6.45%) | 2 (7.41%) | 1 (6.67%) | 1 (10.0%) | 0 (0%) | |
*Global p<0.05.
Mean postoperative visual acuity in patients receiving pars plana vitrectomy and scleral buckle procedures
| Vitrectomy | Scleral buckle | Significance† | |||||||||
| n | Mean (logMAR) | SD (logMAR) | Snellen | Significance* | n | Mean (logMAR) | SD (logMAR) | Snellen | Significance* | ||
| Preoperative | 38 | 1.61 | 0.73 | 20/814 | – | 22 | 0.95 | 0.84 | 20/178 | – | <0.001 |
| POM3 | 31 | 1.23 | 0.75 | 20/339 | 0.050 | 20 | 0.68 | 0.64 | 20/95 | 1.000 | 0.027 |
| POM6 | 30 | 1.10 | 0.80 | 20/251 | 0.011 | 16 | 0.77 | 0.73 | 20/117 | 0.567 | 0.077 |
| POM12 | 26 | 1.05 | 0.80 | 20/224 | 0.012 | 12 | 0.52 | 0.47 | 20/66 | 0.422 | 0.254 |
| Final visit | 38 | 1.19 | 0.98 | 20/309 | 22 | 0.58 | 0.73 | 20/76 | 0.055 | ||
| Global comparison—any change from preoperative: <0.001 | Global comparison—any change from preoperative: 0.002 | ||||||||||
*Within-group comparison from baseline.
†Between-group comparisons between operative procedure.
POM, postoperative month.
Visual outcomes in patients undergoing any rhegmatogenous retinal detachment repair separated by age group
| Patient age group | |||||||||||||||
| 18–29 | 30–39 | 40–50 | |||||||||||||
| n | Mean (logMAR) | SD (logMAR) | Snellen | Significance* | n | Mean (logMAR) | SD (logMAR) | Snellen | Significance* | n | Mean (logMAR) | SD (logMAR) | Snellen | Significance* | |
| Preoperative | 23 | 1.13 | 0.75 | 20/269 | – | 25 | 1.01 | 0.77 | 20/204 | – | 38 | 1.32 | 0.78 | 20/417 | – |
| POM3 | 23 | 1.01 | 0.84 | 20/204 | 0.815 | 23 | 0.94 | 0.77 | 20/174 | 0.561 | 28 | 0.76 | 0.73 | 20/115 | <0.001 |
| POM6 | 16 | 1.1 | 0.73 | 20/251 | 0.385 | 19 | 0.71 | 0.66 | 20/102 | 0.177 | 23 | 0.76 | 0.7 | 20/115 | <0.001 |
| POM12 | 23 | 1.04 | 0.81 | 20/129 | 0.719 | 23 | 0.94 | 0.68 | 20/174 | 0.038 | 30 | 0.85 | 0.74 | 20/141 | <0.001 |
| Final visit | 23 | 0.8 | 0.75 | 20/126 | 25 | 0.6 | 0.69 | 20/79 | 38 | 0.64 | 0.7 | <0.001 | |||
*Within-group comparison from baseline.
POM, postoperative month.
Postoperative complications in patients receiving vitrectomy, scleral buckle and pnuematic retinopexy
| Re-detachment | CME | ERM | Cataract | ||
| Procedure | Vitrectomy | 8 (21.1%) | 4 (10.5%) | 10 (26.3%) | 12 (48.0%) |
| Scleral buckle | 7 (31.8%) | 0 (0) | 1 (4.54%) | 3 (14.3%) | |
| Pneumatic retinopexy | 5 (38.5%) | 0 (0) | 1 (7.7%) | 2 (22.0%) | |
| Combined | 3 (23.1%) | 1 (7.7%) | 3 (23.1%) | 5 (62.5%) | |
Percentages calculated based on total number of patients undergoing each procedure. For cataracts, only phakic patients considered.
CME, Cystitis Macular Edema; ERM, Epiretinal Membrane.