| Literature DB >> 3616138 |
U Wereszczyńska-Siemiatkowska, K Nebendahl, U Pohl, J Otto, H J Groene, H Wilms, P G Lankisch.
Abstract
Buprenorphine (15 micrograms/kg b.wt. per hour) distinctly reduced pain sensitivity in acute 3% sodium-taurocholate pancreatitis in male Wistar rats without interfering with the course of the disease. This was seen by assessment of enzyme elevation in serum and ascites and by histological evaluation of the pancreas. Buprenorphine is therefore recommended for animal experiments to study the effect of therapeutic principles in acute pancreatitis.Entities:
Mesh:
Substances:
Year: 1987 PMID: 3616138 DOI: 10.1007/bf01852085
Source DB: PubMed Journal: Res Exp Med (Berl) ISSN: 0300-9130