| Literature DB >> 36161195 |
Navin Kumar Verma1,2, Si Jia Tan3, John Chen4, Hanrong Chen5, Muhammad Hafiz Ismail6, Scott A Rice6,7, Pablo Bifani8, Sukumar Hariharan9, Vivek Daniel Paul9, Bharathi Sriram10, Linh Chi Dam10, Chia Ching Chan10, Peiying Ho10, Boon Chong Goh10, Shimin Jasmine Chung11,12, Kenneth Choon Meng Goh13, Shu Hua Thong14, Andrea Lay-Hoon Kwa12,14,15, Adam Ostrowski16, Thet Tun Aung17, Halimah Razali18, Shermaine W Y Low1, Mani Shankar Bhattacharyya19, Hemant K Gautam20, Rajamani Lakshminarayanan2, Thomas Sicheritz-Pontén21, Martha R J Clokie22, Wilfried Moreira17, Maurice Adrianus Monique van Steensel1.
Abstract
Bacteriophages and phage-derived proteins are a promising class of antibacterial agents that experience a growing worldwide interest. To map ongoing phage research in Singapore and neighboring countries, Lee Kong Chian School of Medicine, Nanyang Technological University Singapore (NTU) and Yong Loo Lin School of Medicine, National University of Singapore (NUS) recently co-organized a virtual symposium on Bacteriophage and Bacteriophage-Derived Technologies, which was attended by more than 80 participants. Topics were discussed relating to phage life cycles, diversity, the roles of phages in biofilms and the human gut microbiome, engineered phage lysins to combat polymicrobial infections in wounds, and the challenges and prospects of clinical phage therapy. This perspective summarizes major points discussed during the symposium and new perceptions that emerged after the panel discussion. Copyright 2022, Mary Ann Liebert, Inc., publishers.Entities:
Keywords: antimicrobial resistance; ectolysin; filamentous phages; metagenomics; recombinant phage proteins
Year: 2022 PMID： 36161195 PMCID： PMC9436264 DOI： 10.1089/phage.2022.29028.nkv
Source DB: PubMed Journal: Phage (New Rochelle) ISSN： 2641-6530