Literature DB >> 36157146

AIH in HIV: A Very Much Possible Entity.

Saiprasad G Lad1, Kailash Kolhe1, Shamshersingh Chauhan1, Mayur Gattani1, Pratik Sethiya1, Gaurav K Singh1, B Kiran1, Meghraj Ingle1, Vikas Pandey1.   

Abstract

Autoimmune Hepatitis (AIH) is a chronic liver disease Characterized by interface hepatitis, lymphoplasmacytic infiltrate, and hepatic rosettes. HIV infection is a state of immunosuppression; hence, the possibility of AIH is relatively rare, especially in patients with low CD4 counts. Therefore, we present an interesting case series of four patients with autoimmune liver disease with myriad presentations for the first time from India. We propose that despite the rarity of this presentation with immunosuppression, one should never miss such a treatable cause of liver disease leading to good clinical outcomes.
© 2022 Indian National Association for Study of the Liver. Published by Elsevier B.V.

Entities:  

Keywords:  ACLF, Acute on chronic liver failure; AIH, Autoimmune Hepatitis; AKI, Acute kidney injury; ALT, Alanine transaminase; ANA, Antinuclear antibody; ART, Antiretroviral therapy; ASMA, Anti smooth muscle antibody; AST, Aspartate aminotransferase; CAM, Complementary and alternative medications; DILI, Drug-induced liver injury; GGT, Gamma-transferase; HAV, Hepatitis A Virus; HEV, Hepatitis E Virus; HIV, Human immunodeficiency Virus; IRIS, Immune reconstitution inflammatory syndrome; LFT, Liver function test; PHG, portal hypertensive gastropathy; TJLB, Transjugular liver biopsy; autoimmune hepatitis (AIH); cART, Combination antiretroviral therapy; drug-induced liver injury – AIH (DILI-AIH); human immunodeficiency virus (HIV); iAIH, Denovo Idiopathic AIH

Year:  2022        PMID: 36157146      PMCID: PMC9499873          DOI: 10.1016/j.jceh.2022.05.003

Source DB:  PubMed          Journal:  J Clin Exp Hepatol        ISSN: 0973-6883


  6 in total

1.  Autoimmune-like drug-induced liver injury: a review and update for the clinician.

Authors:  Jonathan G Stine; Patrick G Northup
Journal:  Expert Opin Drug Metab Toxicol       Date:  2016-07-21       Impact factor: 4.481

Review 2.  The clinical phenotypes of autoimmune hepatitis: A comprehensive review.

Authors:  Qixia Wang; Fan Yang; Qi Miao; Edward L Krawitt; M Eric Gershwin; Xiong Ma
Journal:  J Autoimmun       Date:  2015-11-21       Impact factor: 7.094

3.  Prevalence and factors associated with liver test abnormalities among human immunodeficiency virus-infected persons.

Authors:  Nancy Crum-Cianflone; Gary Collins; Sheila Medina; Dean Asher; Richard Campin; Mary Bavaro; Braden Hale; Charles Hames
Journal:  Clin Gastroenterol Hepatol       Date:  2009-10-02       Impact factor: 11.382

4.  Autoimmune hepatitis: a manifestation of immune reconstitution inflammatory syndrome in HIV infected patients?

Authors:  Eric Murunga; Monique Andersson; Christo van Rensburg
Journal:  Scand J Gastroenterol       Date:  2016-03-22       Impact factor: 2.423

Review 5.  Autoimmune hepatitis in human immunodeficiency virus-infected patients: A case series and review of the literature.

Authors:  Roongruedee Chaiteerakij; Anapat Sanpawat; Anchalee Avihingsanon; Sombat Treeprasertsuk
Journal:  World J Gastroenterol       Date:  2019-09-21       Impact factor: 5.742

6.  Autoimmune hepatitis in patients with human immunodeficiency virus infection: A systematic review of the published literature.

Authors:  Mohamad Mubder; Mohamed Azab; Mahendran Jayaraj; Chad Cross; Daisy Lankarani; Banreet Dhindsa; Jen-Jung Pan; Gordon Ohning
Journal:  Medicine (Baltimore)       Date:  2019-09       Impact factor: 1.889

  6 in total

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