Literature DB >> 36154620

Mitochondrial Stress Induces an HRI-eIF2α Pathway Protective for Cardiomyopathy.

Siting Zhu1,2, Anh Nguyen1, Jing Pang1, Jun Zhao3, Ze'e Chen1,2, Zhengyu Liang1, Yusu Gu1, Helen Huynh1, Yutong Bao1, Sharon Lee1, Yuval Kluger3, Kunfu Ouyang2, Sylvia M Evans1,4,5, Xi Fang1.   

Abstract

Entities:  

Keywords:  activating transcription factor 4; cardiomyopathy; heme-regulated eIF-2alpha kinase; mitochondria

Mesh：

Substances：

Year:  2022        PMID： 36154620      PMCID： PMC9523491          DOI： 10.1161/CIRCULATIONAHA.122.059594

Source DB:  PubMed          Journal:  Circulation        ISSN： 0009-7322            Impact factor:   39.918


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  5 in total

1.  A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol.

Authors:  Evelyn Fessler; Eva-Maria Eckl; Sabine Schmitt; Igor Alves Mancilla; Matthias F Meyer-Bender; Monika Hanf; Julia Philippou-Massier; Stefan Krebs; Hans Zischka; Lucas T Jae
Journal:  Nature       Date:  2020-03-04       Impact factor: 49.962

Review 2.  The integrated stress response: From mechanism to disease.

Authors:  Mauro Costa-Mattioli; Peter Walter
Journal:  Science       Date:  2020-04-24       Impact factor: 47.728

3.  PTPMT1 Is Required for Embryonic Cardiac Cardiolipin Biosynthesis to Regulate Mitochondrial Morphogenesis and Heart Development.

Authors:  Ze'e Chen; Siting Zhu; Hong Wang; Li Wang; Jianlin Zhang; Yusu Gu; Changming Tan; Mehul Dhanani; Eric Wever; Xinru Wang; Boyu Xie; Shijia Wang; Lei Huang; Antoine H C van Kampen; Jie Liu; Zhen Han; Hemal H Patel; Frédéric M Vaz; Xi Fang; Ju Chen; Kunfu Ouyang
Journal:  Circulation       Date:  2021-08-02       Impact factor: 39.918

4.  Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway.

Authors:  Xiaoyan Guo; Giovanni Aviles; Yi Liu; Ruilin Tian; Bret A Unger; Yu-Hsiu T Lin; Arun P Wiita; Ke Xu; M Almira Correia; Martin Kampmann
Journal:  Nature       Date:  2020-03-04       Impact factor: 49.962

5.  Cardiolipin Remodeling Defects Impair Mitochondrial Architecture and Function in a Murine Model of Barth Syndrome Cardiomyopathy.

Authors:  Siting Zhu; Ze'e Chen; Mason Zhu; Ying Shen; Leonardo J Leon; Liguo Chi; Simone Spinozzi; Changming Tan; Yusu Gu; Anh Nguyen; Yi Zhou; Wei Feng; Frédéric M Vaz; Xiaohong Wang; Asa B Gustafsson; Sylvia M Evans; Ouyang Kunfu; Xi Fang
Journal:  Circ Heart Fail       Date:  2021-06-15       Impact factor: 10.447
  5 in total

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