Harrad Mouna1, Watik Fedoua2, Tangara Omar1, Sami Zineb1, Houssine Boufettal1, Sakher Mahdaui1, Naima Samouh1. 1. Obstetrics and Gynecology Department, Univesity Hospital Ibn Rochd, Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, Morocco. 2. Obstetrics and Gynecology Department, Univesity Hospital Ibn Rochd, Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, Morocco. Electronic address: watik.fedoua@gmail.com.
Abstract
INTRODUCTION: Neuroendocrine carcinomas mainly affect the bronchopulmonary system and the gastrointestinal tract. Mammary localizations are rare. They represent less than 0.1 % of all breast cancers and less than 1 % of neuroendocrine tumors. CASE REPORT: Our case concerns a 50-year-old female patient, who has presented for one year with a rapidly evolving, hard, right breast nodule without associated adenopathy. DISCUSSION: The diagnosis of certainty is based on histological study, and more particularly on immunohistochemical study. Studies concerning this entity are rare and include a small number of cases. We have described a case of triple negative neuroendocrine carcinoma with a high proliferation index. The study of larger series will allow us to better understand their histogenesis as well as their evolutionary profile. CONCLUSION: The treatment of endocrine tumors of the breast is mainly surgical. The indications for chemotherapy and radiotherapy are the same as for other breast cancers.
INTRODUCTION: Neuroendocrine carcinomas mainly affect the bronchopulmonary system and the gastrointestinal tract. Mammary localizations are rare. They represent less than 0.1 % of all breast cancers and less than 1 % of neuroendocrine tumors. CASE REPORT: Our case concerns a 50-year-old female patient, who has presented for one year with a rapidly evolving, hard, right breast nodule without associated adenopathy. DISCUSSION: The diagnosis of certainty is based on histological study, and more particularly on immunohistochemical study. Studies concerning this entity are rare and include a small number of cases. We have described a case of triple negative neuroendocrine carcinoma with a high proliferation index. The study of larger series will allow us to better understand their histogenesis as well as their evolutionary profile. CONCLUSION: The treatment of endocrine tumors of the breast is mainly surgical. The indications for chemotherapy and radiotherapy are the same as for other breast cancers.
Authors: Abid Irshad; Susan J Ackerman; Thomas L Pope; Christopher K Moses; Tihana Rumboldt; Beata Panzegrau Journal: Radiographics Date: 2008 Sep-Oct Impact factor: 5.333