Literature DB >> 36152180

Displacement Binding Assay Using Human Cannabinoid CB2 Receptor-Transfected Cells.

Maria Grazia Cascio1, Pietro Marini1, Roger G Pertwee2.   

Abstract

Displacement binding assays are nonfunctional assays mostly used with the aim of determining whether a certain compound (plant-derived or synthetic) can bind to a specific receptor with high affinity. Here, we describe the displacement binding assay that is carried out with a radioligand and CHO (Chinese Hamster Ovarian) cells stably transfected with the human cannabinoid CB2 receptor.
© 2023. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Affinity; Agonist; Antagonist; Binding; Cannabinoid CB2 receptors; Ligand; Radioligand

Mesh：

Substances：

Year:  2023        PMID： 36152180     DOI： 10.1007/978-1-0716-2728-0_8

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  1 in total

Review 1.  In vitro receptor binding assays: general methods and considerations.

Authors:  H M Bigott-Hennkens; S Dannoon; M R Lewis; S S Jurisson
Journal:  Q J Nucl Med Mol Imaging       Date:  2008-05-13       Impact factor: 2.346
  1 in total

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