Yuanyuan Sun1,2, Xiaodan Jiang3, Liang Xia2, Xulan Tang2, Hongmin Wu2, Huiqun Zhou2, Yanmei Feng2, Zhong Zheng4, Hongjun Dong5. 1. Department of Neurology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, 450053, Henan Province, China. 2. Department of Otolaryngology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Xuhui District, Shanghai, 200233, China. 3. Department of Otolaryngology, Daqing Longnan Hospital, Daqing, 163000, Heilongjiang Province, China. 4. Department of Otolaryngology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Xuhui District, Shanghai, 200233, China. 5127119009@sjtu.edu.cn. 5. Department of Otolaryngology, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, 215600, Jiangsu Province, China. zjgzy052@njucm.edu.cn.
Abstract
INTRODUCTION: This study investigated the effect of sound therapy combined with drug therapy (SDT) on gap detection threshold and speech recognition scores in patients with sudden sensorineural hearing loss (SSNHL). METHODS: Patients with SSNHL were grouped randomly into SDT and drug therapy (DT) groups. All patients received standard drug treatment and patients in the SDT group additionally received sound stimulation for the affected ears for 6 days. Pure tone audiogram, speech recognition scores at normal and time-compressed rates under quiet and noisy conditions, and the gap detection threshold of the SDT and DT groups before treatment and on day 6 and 30 after treatment were compared. RESULTS: There were 20 patients in the SDT group and 24 in the DT group. The pure tone thresholds of affected ears were significantly lower in the SDT group on day 6 after treatment than those in the DT group at 125 and 250 Hz. Significantly lower gap detection thresholds and higher speech recognition scores under noisy conditions were observed at the normal and time-compressed rates in the SDT group than those in the DT group on day 6 and 30 after treatment. Significant correlations were observed between the gap thresholds and speech recognition scores in a noisy environment at normal and time-compressed rates on day 6 and 30. CONCLUSIONS: SDT may improve the recovery of hearing abilities, such as the gap in noise thresholds and speech recognition in noise, in the case of SSNHL. TRIAL REGISTRATION NUMBER: ChiCTR-IOR-17012262.
INTRODUCTION: This study investigated the effect of sound therapy combined with drug therapy (SDT) on gap detection threshold and speech recognition scores in patients with sudden sensorineural hearing loss (SSNHL). METHODS: Patients with SSNHL were grouped randomly into SDT and drug therapy (DT) groups. All patients received standard drug treatment and patients in the SDT group additionally received sound stimulation for the affected ears for 6 days. Pure tone audiogram, speech recognition scores at normal and time-compressed rates under quiet and noisy conditions, and the gap detection threshold of the SDT and DT groups before treatment and on day 6 and 30 after treatment were compared. RESULTS: There were 20 patients in the SDT group and 24 in the DT group. The pure tone thresholds of affected ears were significantly lower in the SDT group on day 6 after treatment than those in the DT group at 125 and 250 Hz. Significantly lower gap detection thresholds and higher speech recognition scores under noisy conditions were observed at the normal and time-compressed rates in the SDT group than those in the DT group on day 6 and 30 after treatment. Significant correlations were observed between the gap thresholds and speech recognition scores in a noisy environment at normal and time-compressed rates on day 6 and 30. CONCLUSIONS: SDT may improve the recovery of hearing abilities, such as the gap in noise thresholds and speech recognition in noise, in the case of SSNHL. TRIAL REGISTRATION NUMBER: ChiCTR-IOR-17012262.
Authors: Sujana S Chandrasekhar; Betty S Tsai Do; Seth R Schwartz; Laura J Bontempo; Erynne A Faucett; Sandra A Finestone; Deena B Hollingsworth; David M Kelley; Steven T Kmucha; Gul Moonis; Gayla L Poling; J Kirk Roberts; Robert J Stachler; Daniel M Zeitler; Maureen D Corrigan; Lorraine C Nnacheta; Lisa Satterfield Journal: Otolaryngol Head Neck Surg Date: 2019-08 Impact factor: 3.497
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