Literature DB >> 361511

A gastrin releasing peptide from the porcine nonantral gastric tissue.

T J McDonald, G Nilsson, M Vagne, M Ghatei, S R Bloom, V Mutt.   

Abstract

This paper presents evidence for the existence in extracts from porcine non-antral gastric tissue of a peptide capable of causing substantial rises of plasma immunoreactive gastrin levels in a dose dependent manner and of stimulation of gastric acid and pepsin secretion. Obtained data show that the peptide is basic and that its gastrin releasing properties are at least partially resistant to atropinisation and beta-receptor blockade. Antrectomy almost eliminates the rise in plasma IRGa when the peptide is administered. The possible relationship of this peptide to amphibian bombesin is discussed.

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Year:  1978        PMID： 361511      PMCID： PMC1412172          DOI： 10.1136/gut.19.9.767

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  29 in total

1.  Effect of duodenal acidification on gastric mucus and acid secretion in conscious cats.

Authors:  M Vagne; G Perret
Journal:  Digestion       Date:  1976       Impact factor: 3.216

2.  THE CONSTITUTION AND PROPERTIES OF TWO GASTRINS EXTRACTED FROM HOG ANTRAL MUCOSA.

Authors:  R A GREGORY; H J TRACY
Journal:  Gut       Date:  1964-04       Impact factor: 23.059

3.  The chemical mechanism of gastric secretion.

Authors:  J S Edkins
Journal:  J Physiol       Date:  1906-03-13       Impact factor: 5.182

4.  Porcine gastric insulin.

Authors:  C Kühl; S L Jensen; O V Nielsen
Journal:  Endocrinology       Date:  1976-12       Impact factor: 4.736

5.  Distribution and release of human pancreatic polypeptide.

Authors:  T E Adrian; S R Bloom; M G Bryant; J M Polak; P H Heitz; A J Barnes
Journal:  Gut       Date:  1976-12       Impact factor: 23.059

Review 6.  Further investigations of intestinal hormonal polypeptides.

Authors:  V Mutt
Journal:  Clin Endocrinol (Oxf)       Date:  1976       Impact factor: 3.478

7.  Stimulation of gastrin secretion in the pig by parathyroid hormone and its inhibition by thyrocalcitonin.

Authors:  R M Bolman; C W Cooper; S C Garner; P L Munson; S A Wells
Journal:  Endocrinology       Date:  1977-04       Impact factor: 4.736

8.  Localization of vasoactive intestinal polypeptide (VIP) to central and peripheral neurons.

Authors:  L I Larsson; J Fahrenkrug; O Schaffalitzky De Muckadell; F Sundler; R Håkanson; J R Rehfeld
Journal:  Proc Natl Acad Sci U S A       Date:  1976-09       Impact factor: 11.205

9.  Characterization of radioimmunoassayable neurotensin in the rat. Its differential distribution in the central nervous system, small intestine, and stomach.

Authors:  R Carraway; S E Leeman
Journal:  J Biol Chem       Date:  1976-11-25       Impact factor: 5.157

10.  Measurement and partial characterization of immunoreactive glucagon in gastrointestinal tissues of dogs.

Authors:  S Morita; K Doi; C C Yip; M Vranic
Journal:  Diabetes       Date:  1976-11       Impact factor: 9.461
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  35 in total

1.  Neuropeptides in the fish gut. An immunohistochemical study of evolutionary patterns.

Authors:  C Bjenning; S Holmgren
Journal:  Histochemistry       Date:  1988

Review 2.  Bombesin-induced gastroprotection.

Authors:  Sonlee D West; David W Mercer
Journal:  Ann Surg       Date:  2005-02       Impact factor: 12.969

3.  Effectiveness of bombesin and Saccharomyces boulardii against the translocation of Candida albicans in the digestive tract in immunosuppressed rats.

Authors:  Cem Algin; Adnan Sahin; Nuri Kiraz; Varol Sahintürk; Enver Ihtiyar
Journal:  Surg Today       Date:  2005       Impact factor: 2.549

4.  Bombesin-like immunoreactivity in the nervous system of hydra.

Authors:  C J Grimmelikhuijzen; G J Dockray; N Yanaihara
Journal:  Histochemistry       Date:  1981

5.  Serum gastrin responses to bombesin and food in patients with hypergastrinemia.

Authors:  J B Jansen; C B Lamers
Journal:  Dig Dis Sci       Date:  1982-04       Impact factor: 3.199

Review 6.  The gastrointestinal endocrine system.

Authors:  N S Track
Journal:  Can Med Assoc J       Date:  1980-02-09       Impact factor: 8.262

7.  Canine bombesin-like gastrin releasing peptides stimulate gastrin release and acid secretion in the dog.

Authors:  N W Bunnett; B Clark; H T Debas; R C Del Milton; T O Kovacs; M S Orloff; T N Pappas; J R Reeve; J E Rivier; J H Walsh
Journal:  J Physiol       Date:  1985-08       Impact factor: 5.182

8.  Comparative effects of bombesin and porcine gastrin-releasing peptide in the dog.

Authors:  J R Lambert; J Hansky; C Soveny; P Hunt
Journal:  Dig Dis Sci       Date:  1984-11       Impact factor: 3.199

9.  Distribution and projections of neurons with immunoreactivity for both gastrin-releasing peptide and bombesin in the guinea-pig small intestine.

Authors:  M Costa; J B Furness; N Yanaihara; C Yanaihara; T W Moody
Journal:  Cell Tissue Res       Date:  1984       Impact factor: 5.249

10.  Tumor-associated macrophages in clear cell renal cell carcinoma express both gastrin-releasing peptide and its receptor: a possible modulatory role of immune effectors cells.

Authors:  Jens Bedke; Bernhard Hemmerlein; Christina Perske; Andreas Gross; Markus Heuser
Journal:  World J Urol       Date:  2009-12-13       Impact factor: 4.226
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