Diana Canetti1,2, Roberta Maria Antonello1, Laura Saderi3, Mara Giro1, Delia Goletti1,4, Loredana Sarmati5, Paola Rodari6, Marialuisa Bocchino7, Miriam Schirò7, Niccolò Riccardi1,8, Giovanni Sotgiu1,9. 1. StopTB Italia Onlus, Milan, Italy. 2. Department of Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy. 3. Clinical Epidemiology and Medical Statistics Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Italy. 4. National Institute for Infectious Diseases (INMI) "L. Spallanzani" - IRCCS, Rome, Italy. 5. Università Tor Vergata, Roma, Italy. 6. Department of Infectious Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy. 7. Section of Respiratory Diseases, Department of Clinical Medicine and Surgery, Monaldi Hospital, University of Naples Federico II, Naples, Italy. 8. Infectious Diseases Unit, Department of Clinical and Experimental Medicine, Azienda Ospedaliera Universitaria Pisana, University of Pisa, Italy. 9. Department of Medical, Surgical and Experimental Sciences, University of Sassari, Italy.
Abstract
Background: SARS-CoV-2 pandemic affected tuberculosis (TB) management. This Italian nationwide survey assessed COVID-19 impact on TB care and outcomes. Materials and methods: Twenty-one hospitals or referral centres fulfilled an online survey. Primary objective was to describe clinical features, outcomes and retention in care in subjects with latent TB infection (LTBI) or disease over the first wave of COVID-19 pandemic. Secondary objectives were the assessment of risk factors, co-morbidities, diagnostics, radiological findings, and outcomes of COVID-19 in the study population. Results: 254 patients with LTBI or active TB were included. In co-infected (SARS-CoV-2, LTBI/TB) patients, recovery occurred in 29/32 (90.6%) cases, death in one case. High retention in care was preserved. Conclusion: in our cohort, outcomes did not seem to be adversely conditioned by incident COVID-19.
Background: SARS-CoV-2 pandemic affected tuberculosis (TB) management. This Italian nationwide survey assessed COVID-19 impact on TB care and outcomes. Materials and methods: Twenty-one hospitals or referral centres fulfilled an online survey. Primary objective was to describe clinical features, outcomes and retention in care in subjects with latent TB infection (LTBI) or disease over the first wave of COVID-19 pandemic. Secondary objectives were the assessment of risk factors, co-morbidities, diagnostics, radiological findings, and outcomes of COVID-19 in the study population. Results: 254 patients with LTBI or active TB were included. In co-infected (SARS-CoV-2, LTBI/TB) patients, recovery occurred in 29/32 (90.6%) cases, death in one case. High retention in care was preserved. Conclusion: in our cohort, outcomes did not seem to be adversely conditioned by incident COVID-19.
Authors: Catherine Riou; Elsa du Bruyn; Cari Stek; Remy Daroowala; Rene T Goliath; Fatima Abrahams; Qonita Said-Hartley; Brian W Allwood; Nei-Yuan Hsiao; Katalin A Wilkinson; Cecilia S Lindestam Arlehamn; Alessandro Sette; Sean Wasserman; Robert J Wilkinson Journal: J Clin Invest Date: 2021-06-15 Impact factor: 14.808
Authors: M L Aznar; J Espinosa-Pereiro; N Saborit; N Jové; F Sánchez Martinez; S Pérez-Recio; A Vitoria; I Sanjoaquin; E Gallardo; J Llenas-García; V Pomar; I O García; J Cacho; Lisbeth Goncalves De Freitas; J V San Martin; J F García Rodriguez; M Á Jiménez-Fuentes; M L De Souza-Galvao; T Tórtola; R Zules; I Molina; Adrián Sánchez-Montalvá Journal: Int J Infect Dis Date: 2021-04-27 Impact factor: 3.623