Literature DB >> 36147757

Subarachnoid Hemorrhage due to Cerebral Cavernous Malformation in a Young Female.

Cleopatra Thurman1,2, Kasim Qureshi2,3, Baljit Deol1,2, Muhammad U Farooq1,2,3.   

Abstract

Cerebral cavernous malformations (CCMs) are usually intraparenchymal lesions commonly associated with intraparenchymal hemorrhage. Extra-axial Lesions are uncommon and have rarely been reported as the cause of aneurysmal like subarachnoid hemorrhage (SAH). We present a 33-years-old female with a past medical history significant for hypertension who presented with acute onset head and neck pain after bending over. En route to the hospital, she had abnormal motor movements suggestive of seizures. Computed tomography (CT) of the head was significant for diffuse aneurysmal like SAH. Head CT angiography (CTA) and catheter digital subtraction angiography (DSA) were both negative for aneurysm. Magnetic resonance imaging (MRI) of the brain showed susceptibility artifact in the right parafalcine frontal lobe suspicious for underlying CCM. This lesion was in the area suspected of having an aneurysm on CT head. The patient was diagnosed with SAH secondary to cavernous malformation mimicking aneurysmal etiology. This case is important as it serves as a good reminder to consider cavernous malformations in the differential in patients presenting with angiogram negative SAH. Diagnosis of this entity has treatment implications including discontinuation of calcium channel blockers if initiated, discussion about duration of anti-seizure medication, in addition to consideration for surgical intervention in select populations.
© The Author(s) 2022.

Entities:  

Keywords:  cavernous angioma; cavernous malformation hemorrhage; subarachnoid hemorrhage

Year:  2022        PMID: 36147757      PMCID: PMC9485698          DOI: 10.1177/19418744221112133

Source DB:  PubMed          Journal:  Neurohospitalist        ISSN: 1941-8744


  10 in total

1.  Non-aneurysmal perimesencephalic subarachnoid hemorrhage caused by a cavernous angioma.

Authors:  Shadi Yaghi; Sowmini Oomman; Salah G Keyrouz
Journal:  Neurocrit Care       Date:  2011-02       Impact factor: 3.210

2.  Ultrastructural and immunocytochemical evidence that an incompetent blood-brain barrier is related to the pathophysiology of cavernous malformations.

Authors:  R E Clatterbuck; C G Eberhart; B J Crain; D Rigamonti
Journal:  J Neurol Neurosurg Psychiatry       Date:  2001-08       Impact factor: 10.154

3.  Value of delayed MRI in angiogram-negative subarachnoid haemorrhage.

Authors:  J Woodfield; N Rane; S Cudlip; J V Byrne
Journal:  Clin Radiol       Date:  2013-12-18       Impact factor: 2.350

4.  Hemorrhage from cerebral cavernous malformations: a systematic pooled analysis.

Authors:  Bradley A Gross; Rose Du
Journal:  J Neurosurg       Date:  2016-05-20       Impact factor: 5.115

5.  Cerebral Angiography for Evaluation of Patients with CT Angiogram-Negative Subarachnoid Hemorrhage: An 11-Year Experience.

Authors:  J J Heit; G T Pastena; R G Nogueira; A J Yoo; T M Leslie-Mazwi; J A Hirsch; J D Rabinov
Journal:  AJNR Am J Neuroradiol       Date:  2015-09-03       Impact factor: 3.825

6.  Intracranial cavernous angioma manifesting as subarachnoid hemorrhage--case report.

Authors:  M Yamamoto; T Fukushima; K Ikeda; S Nagasaka; S Sakamoto; K Oka; M Tomonaga; F Maehara
Journal:  Neurol Med Chir (Tokyo)       Date:  1993-10       Impact factor: 1.742

7.  An analysis of the natural history of cavernous angiomas.

Authors:  O Del Curling; D L Kelly; A D Elster; T E Craven
Journal:  J Neurosurg       Date:  1991-11       Impact factor: 5.115

8.  Atypical causes of nontraumatic intracranial subarachnoid hemorrhage.

Authors:  Mario Nazareno Carvi y Nievas; Eleftherios Archavlis
Journal:  Clin Neurol Neurosurg       Date:  2008-12-30       Impact factor: 1.876

Review 9.  Incidental findings on brain magnetic resonance imaging: systematic review and meta-analysis.

Authors:  Zoe Morris; William N Whiteley; W T Longstreth; Frank Weber; Yi-Chung Lee; Yoshito Tsushima; Hannah Alphs; Susanne C Ladd; Charles Warlow; Joanna M Wardlaw; Rustam Al-Shahi Salman
Journal:  BMJ       Date:  2009-08-17

10.  Cavernous angioma presenting with subarachnoid hemorrhage which was diffusely distributed in the basal cisterns and mimicked intracranial aneurysm rupture.

Authors:  Atsuhito Uneda; Satoru Yabuno; Takahiro Kanda; Kenta Suzuki; Koji Hirashita; Masatoshi Yunoki; Kimihiro Yoshino
Journal:  Surg Neurol Int       Date:  2017-08-22
  10 in total

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