Literature DB >> 36147426

Prevalence and risk factors of post-operative nausea and vomiting in a tertiary-care hospital: A cross-sectional observational study.

Vikas Sinha1, D Vivekanand2, Shalendra Singh3.   

Abstract

Background: Post-operative nausea and vomiting (PONV) is an unpleasant and one of the most distressing symptoms for any patient undergoing surgery. The anaesthetist is usually blamed, despite evidence that PONV results from a variety of factors including patient characteristics, anaesthetic techniques, and the type of surgery and post-operative care. This study had been conducted to find out the current prevalence and to assess various risk factors for PONV in the Indian population.
Methods: All patients above 18 years undergoing non-cardiac surgery under anaesthesia were selected from the daily operation theatre list by a systematic random sampling method. Koivuranta score was used to predict PONV in first 24 h post-operatively.
Results: Prevalence of PONV in the study population was found to be 25.6%. There was association detected between female gender, non-smokers and occurrence of PONV (CI 95%, p ≤ 0.001, 0.005, respectively). PONV was seen to be more common in patients with history of PONV in prior surgeries, in patients who underwent surgery under general anaesthesia and in patients where opioids were used in the post-operative period (95% CI, p ≤ 0.001, 0.001 and 0.001 respectively). General, laparoscopic, abdominal, orthopaedic, obstetric, breast and urological surgeries showed a significant association with occurrence of PONV (95% CI, p ≤ 0.05).
Conclusion: Inspite of use of antiemetics (single or dual) being given as part of the institutional protocol, the incidence of PONV was still high. There is a need to update our knowledge regarding newer antiemetics and their inclusion in PONV management guidelines. There is need for further research to study various other possible risk factors which may contribute to occurrence of PONV.
© 2020 Director General, Armed Forces Medical Services. Published by Elsevier, a division of RELX India Pvt. Ltd.

Entities:  

Keywords:  Emesis; General anaesthesia; Post-operative nausea vomiting

Year:  2020        PMID: 36147426      PMCID: PMC9485772          DOI: 10.1016/j.mjafi.2020.10.024

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN: 0377-1237


  17 in total

Review 1.  Postoperative nausea and vomiting and outcome.

Authors:  Phillip E Scuderi; Lydia A Conlay
Journal:  Int Anesthesiol Clin       Date:  2003

Review 2.  Nausea and vomiting after surgery under general anesthesia: an evidence-based review concerning risk assessment, prevention, and treatment.

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Journal:  Anesthesiology       Date:  1999-07       Impact factor: 7.892

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Authors:  Tatjana Šimurina; Boris Mraovic; Neven Skitarelić; Tatjana Andabaka; Zdenko Sonicki
Journal:  J Clin Anesth       Date:  2012-03-28       Impact factor: 9.452

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Authors:  Tong J Gan
Journal:  Anesth Analg       Date:  2006-06       Impact factor: 5.108

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Authors:  L H Eberhart; J Högel; W Seeling; A M Staack; G Geldner; M Georgieff
Journal:  Acta Anaesthesiol Scand       Date:  2000-04       Impact factor: 2.105

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Authors:  M M Cohen; P G Duncan; D P DeBoer; W A Tweed
Journal:  Anesth Analg       Date:  1994-01       Impact factor: 5.108

10.  Volatile anaesthetics may be the main cause of early but not delayed postoperative vomiting: a randomized controlled trial of factorial design.

Authors:  C C Apfel; P Kranke; M H Katz; C Goepfert; T Papenfuss; S Rauch; R Heineck; C A Greim; N Roewer
Journal:  Br J Anaesth       Date:  2002-05       Impact factor: 9.166

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