Literature DB >> 36147425

Acanthosis nigricans in Insulinoma: Reversible experiments of the nature.

Vijay Sheker R Danda1, Paidipally Srinivas Rao1, Chaitanya Konda1, Piyush Lodha1.   

Abstract

Acanthosis Nigricans is considered to be a skin marker of insulin resistance and atherosclerosis. It is rarely reported in cases of insulinoma where there is marked hyperinsulinaemia. We report two cases of insulinoma with acanthosis nigricans which regressed, concomitant with significant weight loss and reduction in blood pressure following surgical resection. This strengthens the hypothesis that hyperinsulinaemia is responsible for Acanthosis nigricans and atherosclerotic risk factors.
© 2019 Armed Forces Medical Services (AFMS).

Entities:  

Keywords:  Acanthosis nigricans; Atherosclerosis; Diabetes; Insulinoma; Regression

Year:  2019        PMID： 36147425      PMCID： PMC9485756          DOI： 10.1016/j.mjafi.2019.06.002

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN： 0377-1237


  10 in total

1.  Clearance of acanthosis nigricans associated with the HAIR-AN syndrome after partial pancreatectomy: an 11-year follow-up.

Authors:  S L Pfeifer; R M Wilson; D J Gawkrodger
Journal:  Postgrad Med J       Date:  1999-07       Impact factor: 2.401

Review 2.  Excess insulin binding to insulin-like growth factor receptors: proposed mechanism for acanthosis nigricans.

Authors:  P D Cruz; J A Hud
Journal:  J Invest Dermatol       Date:  1992-06       Impact factor: 8.551

3.  Acanthosis nigricans in insulinoma: before and after successful surgical enucleation.

Authors:  Shinjan Patra; Partha Pratim Chakraborty; Himanshu Barman; Gouranga Santra
Journal:  BMJ Case Rep       Date:  2016-11-11

4.  Functioning insulinoma--incidence, recurrence, and long-term survival of patients: a 60-year study.

Authors:  F J Service; M M McMahon; P C O'Brien; D J Ballard
Journal:  Mayo Clin Proc       Date:  1991-07       Impact factor: 7.616

5.  Insulinoma: Diagnosis and surgical treatment. Retrospective analysis of 31 cases.

Authors:  Viveka P Jyotsna; Neil Rangel; Sujoy Pal; Ashu Seith; Peush Sahni; A C Ammini
Journal:  Indian J Gastroenterol       Date:  2006 Sep-Oct

6.  Clearance of acanthosis nigricans associated with insulinoma following surgical resection.

Authors:  S Ghosh; B Roychowdhury; S Mukhopadhyay; S Chowdhury
Journal:  QJM       Date:  2008-07-31

Review 7.  Hypoglycemia, diabetes, and cardiovascular events.

Authors:  Cyrus V Desouza; Geremia B Bolli; Vivian Fonseca
Journal:  Diabetes Care       Date:  2010-06       Impact factor: 17.152

8.  Evaluation of insulin resistance in obese women with and without acanthosis nigricans.

Authors:  Giti Sadeghian; Hengameh Ziaie; Masoud Amini; Mohhamad Ali Nilfroushzadeh
Journal:  J Dermatol       Date:  2009-04       Impact factor: 4.005

9.  A case of ectopic adrenocorticotropic hormone-producing pancreatic neuroendocrine tumor with multiple liver metastases.

Authors:  Tatsuya Kondo; Rina Matsuyama; Hiroshi Ashihara; Yasuto Matsuo; Kazunari Sasaki; Rieko Goto; Kaoru Ono; Yuki Takaki; Yumi Honda; Ken-Ichi Iyama; Junji Kawashima; Hiroyuki Motoshima; Kaku Tsuruzoe; Nobuhiro Miyamura; Eiichi Araki
Journal:  Endocr J       Date:  2009-12-22       Impact factor: 2.349

Review 10.  An approach to acanthosis nigricans.

Authors:  Meghana Madhukar Phiske
Journal:  Indian Dermatol Online J       Date:  2014-07
  10 in total

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