Ankita Singh1, Poninder Kumar2, Preema Sinha3, Jaya Kaushik4, D Srujana5, Rakesh Shetty1, Divya Kochhar1, Durga Madhab Tripathy6. 1. Resident, Department of Ophthalmology, Armed Forces Medical College, Pune, India. 2. Professor & Head, Department of Ophthalmology, Armed Forces Medical College, Pune, India. 3. Professor & Head (Dermatology), Base Hospital, Lucknow, India. 4. Professor, Department of Ophthalmology, Armed Forces Medical College, Pune, India. 5. Associate Professor, Department of Ophthalmology, Armed Forces Medical College, Pune, India. 6. Resident, Department of Dermatology, Armed Forces Medical College, Pune, India.
Abstract
Background: The aim of the study is to observe the ocular manifestation in patients of psoriasis. Methods: All the diagnosed cases of Psoriasis by the dermatology department of this tertiary care hospital were included in this study. Relevant details of the history pertaining to disease duration, type of psoriasis, and treatment undertaken including ocular symptoms were obtained. Disease severity was quantified using the PASI score. Complete ocular examination including intraocular pressure, Schirmer I and II tests, Tear Film Breakup Tme (TBUT); was carried out for all the patients. Results: Of 126 patients of psoriasis, ocular manifestations were seen in 76 patients (60.3%). Dry eyes (27%) and blepharitis (15.9%) were the most common ocular manifestations. Uveitis was seen in 3.2% of the patients of which 75% patients were HA B27-positive psoriatic arthritis, which was statistically significant (p = 0.001). There was no statistical correlation between duration of the disease and ocular manifestations (p value is 0.077 using chi square test). The ocular manifestations were more common in patients with PASI score 10 when compared with the patients with PASI score 10 (p value = 0.028) which was statistically significant. Conclusions: In our study, prevalence of ocular manifestation was 60.3% which increased with the increasing PASI score. Dry eyes and blepharitis were the most common manifestations. Hence, routine ocular examination is recommended in patients with psoriasis.
Background: The aim of the study is to observe the ocular manifestation in patients of psoriasis. Methods: All the diagnosed cases of Psoriasis by the dermatology department of this tertiary care hospital were included in this study. Relevant details of the history pertaining to disease duration, type of psoriasis, and treatment undertaken including ocular symptoms were obtained. Disease severity was quantified using the PASI score. Complete ocular examination including intraocular pressure, Schirmer I and II tests, Tear Film Breakup Tme (TBUT); was carried out for all the patients. Results: Of 126 patients of psoriasis, ocular manifestations were seen in 76 patients (60.3%). Dry eyes (27%) and blepharitis (15.9%) were the most common ocular manifestations. Uveitis was seen in 3.2% of the patients of which 75% patients were HA B27-positive psoriatic arthritis, which was statistically significant (p = 0.001). There was no statistical correlation between duration of the disease and ocular manifestations (p value is 0.077 using chi square test). The ocular manifestations were more common in patients with PASI score 10 when compared with the patients with PASI score 10 (p value = 0.028) which was statistically significant. Conclusions: In our study, prevalence of ocular manifestation was 60.3% which increased with the increasing PASI score. Dry eyes and blepharitis were the most common manifestations. Hence, routine ocular examination is recommended in patients with psoriasis.
Authors: Marinka Twilt; Marietta Swart van den Berg; Jan C van Meurs; Rebecca ten Cate; Lisette W A van Suijlekom-Smit Journal: Eur J Pediatr Date: 2003-07-03 Impact factor: 3.183
Authors: Bruce Strober; Jeffrey D Greenberg; Chitra Karki; Marc Mason; Ning Guo; Peter Hur; Yang Zhao; Vivian Herrera; Feng Lin; Mark Lebwohl Journal: BMJ Open Date: 2019-04-20 Impact factor: 2.692