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Literature DB >> 361314

Complement-mediated immune mechanisms in renal infection. II. Effect of decomplementation.

Abstract

Animals were depleted of complement using cobra venom factor and the influence of complement depletion on the course of renal infection was studied. Complement depletion markedly increased the susceptibility of renal tissue to a challenge with an E. coli strain sensitive to the bactericidal activity of normal serum, but did not influence the outcome of a challenge with a serum-resistant strain of E. coli. These observations are consistent with the hypothesis that complement-mediated host immune mechanisms do play a role in the biology of renal infection and are an important component of the host's immune response in pyelonephritis.

Entities: Disease Species

Mesh：

Substances：

Year: 1978 PMID： 361314 PMCID： PMC1537524

Source DB: PubMed Journal: Clin Exp Immunol ISSN： 0009-9104 Impact factor: 4.330

12 in total

1. Exchanges of water and ions by kidney slices determined by a balance method.

Authors: J R ROBINSON
Journal: J Physiol Date: 1961-10 Impact factor: 5.182

2. Experimental pyelonephritis: a new method for inducing pyelonephritis in the rat.

Authors: T E Miller; K B Robinson
Journal: J Infect Dis Date: 1973-03 Impact factor: 5.226

3. Serum bactericidal activity in patients with upper and lower urinary tract infections.

Authors: P E Gower; P W Taylor; K G Koutsaimanis; A P Roberts
Journal: Clin Sci Date: 1972-07 Impact factor: 6.124

4. An antibactericidal factor in the serum of two patients with infections of the upper urinary tract.

Authors: P W Taylor
Journal: Clin Sci Date: 1972-07 Impact factor: 6.124

5. A factor in the serum of patients with persisting infection that inhibits the bactericidal activity of normal serum against the organism that is causing the infection.

Authors: B A Waisbren; I Brown
Journal: J Immunol Date: 1966-09 Impact factor: 5.422

6. Complement-mediated immune mechanisms in renal infection.

Authors: D J Ormrod; T E Miller
Journal: Clin Exp Immunol Date: 1978-07 Impact factor: 4.330

7. C3 shunt activation in human serum chelated with EGTA.

Authors: D P Fine; S R Marney; D G Colley; J S Sergent; R M Des Prez
Journal: J Immunol Date: 1972-10 Impact factor: 5.422

8. Two anticomplementary factors in cobra venom: hemolysis of guinea pig erythrocytes by one of them.

Authors: M Ballow; C G Cochrane
Journal: J Immunol Date: 1969-11 Impact factor: 5.422

9. THE EPIDEMIOLOGY OF NONENTERIC ESCHERICHIA COLI INFECTIONS. II. RELATIONSHIP OF PREVALENCE OF E. COLI IN URINARY INFECTIONS TO THE BACTERICIDAL EFFECT OF HUMAN SERUM.

Authors: H KIMBALL; M GARCIA; R G PETERSDORF
Journal: J Lab Clin Med Date: 1964-06

Review 8. Collectin-11 (CL-11) Is a Major Sentinel at Epithelial Surfaces and Key Pattern Recognition Molecule in Complement-Mediated Ischaemic Injury.

Authors: Christopher L Nauser; Mark C Howard; Giorgia Fanelli; Conrad A Farrar; Steven Sacks
Journal: Front Immunol Date: 2018-09-06 Impact factor: 7.561

8 in total

Complement-mediated immune mechanisms in renal infection. II. Effect of decomplementation.

1. Exchanges of water and ions by kidney slices determined by a balance method.

2. Experimental pyelonephritis: a new method for inducing pyelonephritis in the rat.

3. Serum bactericidal activity in patients with upper and lower urinary tract infections.

4. An antibactericidal factor in the serum of two patients with infections of the upper urinary tract.

5. A factor in the serum of patients with persisting infection that inhibits the bactericidal activity of normal serum against the organism that is causing the infection.

6. Complement-mediated immune mechanisms in renal infection.

7. C3 shunt activation in human serum chelated with EGTA.

8. Two anticomplementary factors in cobra venom: hemolysis of guinea pig erythrocytes by one of them.

9. THE EPIDEMIOLOGY OF NONENTERIC ESCHERICHIA COLI INFECTIONS. II. RELATIONSHIP OF PREVALENCE OF E. COLI IN URINARY INFECTIONS TO THE BACTERICIDAL EFFECT OF HUMAN SERUM.

10. The anticomplementary effect of kidney tissue; its association with ammonia production.

1. Cellular basis of host defence in pyelonephritis. II. Acute infection.

Review 2. Bactericidal and bacteriolytic activity of serum against gram-negative bacteria.

3. Role of complement in chemotaxis: study of a localized infection.

Review 4. Virulence factors in Escherichia coli urinary tract infection.

5. P-fimbriae studies on the diagnosis and prevention of acute pyelonephritis.

6. P-fimbriae studies on the diagnosis and prevention of acute pyelonephritis.

7. Valsartan Alleviates Insulin Resistance in Skeletal Muscle of Chronic Renal Failure Rats.

Review 8. Collectin-11 (CL-11) Is a Major Sentinel at Epithelial Surfaces and Key Pattern Recognition Molecule in Complement-Mediated Ischaemic Injury.