Literature DB >> 3612502

OMNE: a new robust membership-set estimator for the parameters of nonlinear models.

H Lahanier, E Walter, R Gomeni.   

Abstract

A new method for estimating parameters and their uncertainty is presented. Data are assumed to be corrupted by a noise whose statistical properties are unknown but for which bounds are available at each sampling time. The method estimates the set of all parameter vectors consistent with this hypothesis. Its results are compared with those of the weighted least squares, extended least squares, and biweight robust regression approaches on two data sets, one of which includes 33% outliers. On the basis of these preliminary results, the new method appears to have attractive properties of reliability and robustness.

Mesh:

Year:  1987        PMID: 3612502     DOI: 10.1007/bf01062344

Source DB:  PubMed          Journal:  J Pharmacokinet Biopharm        ISSN: 0090-466X


  2 in total

1.  Extended least squares nonlinear regression: a possible solution to the "choice of weights" problem in analysis of individual pharmacokinetic data.

Authors:  C C Peck; S L Beal; L B Sheiner; A I Nichols
Journal:  J Pharmacokinet Biopharm       Date:  1984-10

2.  Analysis of pharmacokinetic data using parametric models--1: Regression models.

Authors:  L B Sheiner
Journal:  J Pharmacokinet Biopharm       Date:  1984-02
  2 in total
  1 in total

1.  Predictive performance of a semiparametric method to estimate population pharmacokinetic parameters using NONMEM.

Authors:  F Bressolle; R Gomeni
Journal:  J Pharmacokinet Biopharm       Date:  1998-06
  1 in total

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