Literature DB >> 361156

Dexamethasone in acute stroke.

G Mulley, R G Wilcox, J R Mitchell.   

Abstract

Over 13 months 118 patients admitted to hospital with acute stroke were allocated at random to treatment with either dexamethasone or placebo. At one year there was no significant difference in the numbers of survivors or in the quality of life between the two groups. The results suggest that there is no indication for the routine administration of dexamethasone to a heterogeneous group of patients with stroke.

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Year:  1978        PMID： 361156      PMCID： PMC1607934          DOI： 10.1136/bmj.2.6143.994

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  8 in total

1.  Effect of cortisone and hydrocortisone in hemiplegia after cerebral infarction. I. Preliminary report, with special reference to spasticity.

Authors:  R F SHEELY; C H JOHNSON; J J BAKER; R HARBAUGH
Journal:  J Am Med Assoc       Date:  1955-07-09

2.  Cortisone in immediate therapy of apoplectic stroke.

Authors:  H I RUSSEK; A S RUSSEK; B L ZOHMAN
Journal:  J Am Med Assoc       Date:  1955-09-10

3.  Dexamethasone as treatment in cerebrovascular disease. 2. A controlled study in acute cerebral infarction.

Authors:  R B Bauer; H Tellez
Journal:  Stroke       Date:  1973 Jul-Aug       Impact factor: 7.914

4.  Double-blind study of the effects of dexamethasone on acute stroke.

Authors:  B M Patten; J Mendell; B Bruun; W Curtin; S Carter
Journal:  Neurology       Date:  1972-04       Impact factor: 9.910

5.  Letter: Anti-oedema treatment of completed stroke.

Authors:  L Candelise; A Colombo; H Spinnler
Journal:  Lancet       Date:  1974-04-27       Impact factor: 79.321

6.  The influence of adrenocortical steroids on severe cerebrovascular accidents.

Authors:  M K Rubinstein
Journal:  J Nerv Ment Dis       Date:  1965-09       Impact factor: 2.254

7.  Massive cerebral infarction with severe brain swelling: a clinicopathological study.

Authors:  L K Ng; J Nimmannitya
Journal:  Stroke       Date:  1970 May-Jun       Impact factor: 7.914

8.  Steroid therapy in acute cerebral infarction.

Authors:  J W Norris
Journal:  Arch Neurol       Date:  1976-01
  8 in total
  18 in total

1.  Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids.

Authors:  Florian P Limbourg; Zhihong Huang; Jean-Christophe Plumier; Tommaso Simoncini; Masayuki Fujioka; Jan Tuckermann; Günther Schütz; Michael A Moskowitz; James K Liao
Journal:  J Clin Invest       Date:  2002-12       Impact factor: 14.808

Review 2.  Clinical trials for cytoprotection in stroke.

Authors:  Lise A Labiche; James C Grotta
Journal:  NeuroRx       Date:  2004-01

3.  The diagnostic challenge of acute polyarthritis.

Authors:  I A Wamuo; P I Pitt
Journal:  Ann Rheum Dis       Date:  1996-05       Impact factor: 19.103

4.  High dose steroid treatment in cerebral infarction.

Authors:  J W Norris; V C Hachinski
Journal:  Br Med J (Clin Res Ed)       Date:  1986-01-04

Review 5.  Drug treatment of stroke. Current status and future prospects.

Authors:  C A Sila; A J Furlan
Journal:  Drugs       Date:  1988-04       Impact factor: 9.546

6.  Study of the prevalence of atrial fibrillation in general practice patients over 65 years of age.

Authors:  J D Hill; E M Mottram; P D Killeen
Journal:  J R Coll Gen Pract       Date:  1987-04

7.  The combined effects of hypertension, hemodilution, and osmotherapy on the metabolic sequelae of acute experimental cerebral ischemia.

Authors:  S Ehteshami; B S Aspey; C M Hurst; A L McCoy; M J Harrison
Journal:  Metab Brain Dis       Date:  1988-09       Impact factor: 3.584

8.  New approach to treatment of recent stroke.

Authors:  T Steiner; R Capildeo; F C Rose
Journal:  Br Med J       Date:  1979-02-10

9.  Implications of immune system in stroke for novel therapeutic approaches.

Authors:  Aaron A Hall; Keith R Pennypacker
Journal:  Transl Stroke Res       Date:  2010-01-13       Impact factor: 6.829

10.  Outcome of acute supratentorial cerebral infarction in patients under 60. Development of a prognostic grading system.

Authors:  H J Steiger
Journal:  Acta Neurochir (Wien)       Date:  1991       Impact factor: 2.216
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