Literature DB >> 36115121

A young patient with prostatic carcinoma with testicular metastasis.

B Balagobi1, S Gobishangar2, S T Sarma2, R T Brammah3, A Jenil4.   

Abstract

Prostate cancer is one of the most frequent cancers in males and commonly a disease of the older population, but it is increasingly seen among older adolescents and young adults. The common sites of metastasis of prostatic carcinoma are bones and regional lymph nodes. Testicular metastasis from prostatic carcinoma is an infrequent presentation. We report a case of a young patient with prostatic carcinoma and multiple metastases, including bilateral testis. A 40-year-old male presented with lower urinary tract voiding symptoms and back pain for three months. His prostate-specific antigen level was elevated at 13.98 ng/ml. A magnetic resonance imaging of the prostate revealed two PIRADS V lesions and metastases in multiple bones and regional lymph nodes. On follow up, the patient complained of bilateral testicular swelling and ultrasound scan of the testes revealed bilateral testicular metastasis. Fine needle aspiration cytology of right-side testicular lesion revealed malignant cells compatible with metastasis from prostate cancer. Later involvement of multilevel vertebral and skull metastases was identified by magnetic resonance imaging. A T3bN1M1c staging of prostate cancer was made, androgen deprivation therapy followed by chemo and radiotherapy was instituted, following extensive discussion with the patient. Unfortunately the patient succumbed to the illness during the course of treatment. This case report is of a patient with rare presentation of bilateral testicular metastasis with prostate cancer in young age.
Copyright © 2022. Published by Elsevier Ltd.

Entities:  

Keywords:  Case report; Metastasis; Prostate cancer; Secondary; Testicular; Young

Year:  2022        PMID: 36115121      PMCID: PMC9568776          DOI: 10.1016/j.ijscr.2022.107653

Source DB:  PubMed          Journal:  Int J Surg Case Rep        ISSN: 2210-2612


  13 in total

1.  Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients.

Authors:  L Bubendorf; A Schöpfer; U Wagner; G Sauter; H Moch; N Willi; T C Gasser; M J Mihatsch
Journal:  Hum Pathol       Date:  2000-05       Impact factor: 3.466

Review 2.  Young-age prostate cancer.

Authors:  S Hussein; S Satturwar; T Van der Kwast
Journal:  J Clin Pathol       Date:  2015-04-02       Impact factor: 3.411

3.  Prostate cancer in young men: An emerging young adult and older adolescent challenge.

Authors:  Archie Bleyer; Filippo Spreafico; Ronald Barr
Journal:  Cancer       Date:  2019-09-25       Impact factor: 6.860

4.  Testicular metastases from prostate carcinoma.

Authors:  Harrina Erlianti Rahardjo; Rainy Umbas; Himawan Sutisna
Journal:  Asian J Surg       Date:  2010-07       Impact factor: 2.767

5.  Testicular metastases: a poor prognostic factor in patients with advanced prostate cancer.

Authors:  Fernando Korkes; Renato Gasperini; Karen Levy Korkes; Deusdedit Cortez Vieira Silva Neto; Marilia Germanos Castro
Journal:  World J Urol       Date:  2008-09-02       Impact factor: 4.226

6.  Metastatic tumours in the testis.

Authors:  A J Tiltman
Journal:  Histopathology       Date:  1979-01       Impact factor: 5.087

7.  Testicular Metastasis From Prostatic Adenocarcinoma Presenting as Recurrent Epididymo-orchitis.

Authors:  Kyle M Waisanen; Tijani Osumah; Sneha S Vaish
Journal:  Urology       Date:  2017-07-28       Impact factor: 2.649

8.  Prostate cancer testicular metastasis: Are they underestimated? Case report and analysis of the literature.

Authors:  Salvatore Smelzo; Guglielmo Mantica; Roberta Lucianò; Nazario Pio Tenace; Davide De Marchi; Giovannalberto Pini; Giovanni Passaretti; Andrea Losa; Franco Gaboardi
Journal:  Urologia       Date:  2021-04-08

9.  Testicular metastasis of prostate cancer: a case report.

Authors:  Ayumu Kusaka; Takuya Koie; Hayato Yamamoto; Itsuto Hamano; Takahiro Yoneyama; Yasuhiro Hashimoto; Chikara Ohyama; Yuki Tobisawa; Tohru Yoneyama
Journal:  Case Rep Oncol       Date:  2014-09-18

Review 10.  Androgen deprivation therapy and side effects: are GnRH antagonists safer?

Authors:  Stephen J Freedland; Per-Anders Abrahamsson
Journal:  Asian J Androl       Date:  2021 Jan-Feb       Impact factor: 3.285

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