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10 in total

1. The pharmacokinetics and activation of proguanil in man: consequences of variability in drug metabolism.

Authors: N A Helsby; S A Ward; G Edwards; R E Howells; A M Breckenridge
Journal: Br J Clin Pharmacol Date: 1990-10 Impact factor: 4.335

2. Inter-subject variability in the metabolism of proguanil to the active metabolite cycloguanil in man.

Authors: S A Ward; W M Watkins; E Mberu; J E Saunders; D K Koech; H M Gilles; R E Howells; A M Breckenridge
Journal: Br J Clin Pharmacol Date: 1989-06 Impact factor: 4.335

3. The pharmacokinetics and pharmacodynamics of atovaquone and proguanil for the treatment of uncomplicated falciparum malaria in third-trimester pregnant women.

Authors: K Na-Bangchang; C Manyando; R Ruengweerayut; D Kioy; M Mulenga; G B Miller; J Konsil
Journal: Eur J Clin Pharmacol Date: 2005-07-23 Impact factor: 2.953

4. Evidence for the polymorphic oxidation of debrisoquine and proguanil in a Khmer (Cambodian) population.

Authors: S Wanwimolruk; M R Thou; D J Woods
Journal: Br J Clin Pharmacol Date: 1995-08 Impact factor: 4.335

5. Single dose pharmacokinetics of proguanil and its metabolites in pregnancy.

Authors: J Wangboonskul; N J White; F Nosten; F ter Kuile; R R Moody; R B Taylor
Journal: Eur J Clin Pharmacol Date: 1993 Impact factor: 2.953

6. In vitro metabolism of the biguanide antimalarials in human liver microsomes: evidence for a role of the mephenytoin hydroxylase (P450 MP) enzyme.

Authors: N A Helsby; S A Ward; R E Howells; A M Breckenridge
Journal: Br J Clin Pharmacol Date: 1990-08 Impact factor: 4.335

7. The activation of the biguanide antimalarial proguanil co-segregates with the mephenytoin oxidation polymorphism--a panel study.

Authors: S A Ward; N A Helsby; E Skjelbo; K Brøsen; L F Gram; A M Breckenridge
Journal: Br J Clin Pharmacol Date: 1991-06 Impact factor: 4.335

Determination of proguanil and its metabolites cycloguanil and 4-chlorophenylbiguanide in plasma, whole blood and urine by high-performance liquid chromatography.