Literature DB >> 36111569

Biomarkers in oral immunotherapy.

Haitao Zhu1, Kaifa Tang2, Guoqiang Chen1, Zhongwei Liu3.   

Abstract

Food allergy (FA) is a global health problem that affects a large population, and thus effective treatment is highly desirable. Oral immunotherapy (OIT) has been showing reasonable efficacy and favorable safety in most FA subjects. Dependable biomarkers are needed for treatment assessment and outcome prediction during OIT. Several immunological indicators have been used as biomarkers in OIT, such as skin prick tests, basophil and mast cell reactivity, T cell and B cell responses, allergen-specific antibody levels, and cytokines. Other novel indicators also could be potential biomarkers. In this review, we discuss and assess the application of various immunological indicators as biomarkers for OIT.

Entities:  

Keywords:  Biomarker; Desensitization; Food allergy; Immune tolerance; Oral immunotherapy

Mesh：

Substances：

Year:  2022        PMID： 36111569      PMCID： PMC9483607          DOI： 10.1631/jzus.B2200047

Source DB:  PubMed          Journal:  J Zhejiang Univ Sci B        ISSN： 1673-1581            Impact factor:   5.552


  221 in total

1.  Artificial sweeteners and mixture of food additives cause to break oral tolerance and induce food allergy in murine oral tolerance model for food allergy.

Authors:  H Yamashita; H Matsuhara; S Miotani; Y Sako; T Matsui; H Tanaka; N Inagaki
Journal:  Clin Exp Allergy       Date:  2017-05-08       Impact factor: 5.018

2.  Expression of activation markers on basophils in a controlled model of anaphylaxis.

Authors:  Laura M Gober; John A Eckman; Patricia M Sterba; Kavitha Vasagar; John T Schroeder; David B K Golden; Sarbjit S Saini
Journal:  J Allergy Clin Immunol       Date:  2007-03-01       Impact factor: 10.793

3.  Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria.

Authors:  Usriansyah Hadis; Benjamin Wahl; Olga Schulz; Matthias Hardtke-Wolenski; Angela Schippers; Norbert Wagner; Werner Müller; Tim Sparwasser; Reinhold Förster; Oliver Pabst
Journal:  Immunity       Date:  2011-02-17       Impact factor: 31.745

4.  Fcγ receptors inhibit mouse and human basophil activation.

Authors:  Lydie Cassard; Friederike Jönsson; Ségolène Arnaud; Marc Daëron
Journal:  J Immunol       Date:  2012-08-20       Impact factor: 5.422

5.  Modulation of dendritic cell innate and adaptive immune functions by oral and sublingual immunotherapy.

Authors:  Pamela A Frischmeyer-Guerrerio; Corinne A Keet; Anthony L Guerrerio; Kristin L Chichester; Anja P Bieneman; Robert G Hamilton; Robert A Wood; John T Schroeder
Journal:  Clin Immunol       Date:  2014-08-27       Impact factor: 3.969

6.  Sphingosine 1-phosphate-mediated trafficking of pathogenic Th2 and mast cells for the control of food allergy.

Authors:  Yosuke Kurashima; Jun Kunisawa; Morio Higuchi; Masashi Gohda; Izumi Ishikawa; Naoko Takayama; Miki Shimizu; Hiroshi Kiyono
Journal:  J Immunol       Date:  2007-08-01       Impact factor: 5.422

7.  Effect of anti-IgE therapy in patients with peanut allergy.

Authors:  Donald Y M Leung; Hugh A Sampson; John W Yunginger; A Wesley Burks; Lynda C Schneider; Cornelis H Wortel; Frances M Davis; John D Hyun; William R Shanahan
Journal:  N Engl J Med       Date:  2003-03-10       Impact factor: 91.245

8.  Orally-Induced Intestinal CD4+ CD25+ FoxP3+ Treg Controlled Undesired Responses towards Oral Antigens and Effectively Dampened Food Allergic Reactions.

Authors:  Paola Lorena Smaldini; María Lucía Orsini Delgado; Carlos Alberto Fossati; Guillermo Horacio Docena
Journal:  PLoS One       Date:  2015-10-30       Impact factor: 3.240

9.  Investigation of Basophil Activation Test for Diagnosing Milk and Egg Allergy in Younger Children.

Authors:  Yoon Hee Kim; Young Suh Kim; Younhee Park; Soo Yeon Kim; Kyung Won Kim; Hyon Suk Kim; Myung Hyun Sohn
Journal:  J Clin Med       Date:  2020-12-05       Impact factor: 4.241

10.  Single B-cell deconvolution of peanut-specific antibody responses in allergic patients.

Authors:  Ramona A Hoh; Shilpa A Joshi; Yi Liu; Chen Wang; Krishna M Roskin; Ji-Yeun Lee; Tho Pham; Tim J Looney; Katherine J L Jackson; Vaishali P Dixit; Jasmine King; Shu-Chen Lyu; Jennifer Jenks; Robert G Hamilton; Kari C Nadeau; Scott D Boyd
Journal:  J Allergy Clin Immunol       Date:  2015-07-04       Impact factor: 10.793
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