Literature DB >> 36111083

Anal Squamous Intraepithelial Lesions and Anal Cancer Management in Low Resource Settings.

Alexander T Hawkins1, Sandy H Fang2.   

Abstract

A low resource setting (LRS) is defined as a health care system which does not meet the criteria defined by the World Health Organization (WHO) or other national/international organizations in the following areas: infrastructure, materials, and human resources. 1 Patients encounter barriers which limit their access to care and services that are considered standard of care. While LRS is most commonly associated with developing countries, it is easy to overlook communities in developed countries which lack the financial resources to afford basic health care. This article describes the societal implications and barriers to care for both squamous intraepithelial lesions (SILs) and anal cancer in LRS, the existing screening/surveillance approaches, available treatment approaches to anal cancer, and it also discusses potential evidence-based approaches to bridge the gap for these disparities in anal cancer care. Thieme. All rights reserved.

Entities:  

Keywords:  anal cancer; high-resolution anoscopy; squamous intraepithelial lesions

Year:  2022        PMID: 36111083      PMCID: PMC9470285          DOI: 10.1055/s-0042-1746188

Source DB:  PubMed          Journal:  Clin Colon Rectal Surg        ISSN: 1530-9681


  54 in total

1.  A double-blind, randomized controlled trial of the use of imiquimod cream for the treatment of anal canal high-grade anal intraepithelial neoplasia in HIV-positive MSM on HAART, with long-term follow-up data including the use of open-label imiquimod.

Authors:  Paul A Fox; Mayura Nathan; Nicholas Francis; Naveena Singh; Justin Weir; Glen Dixon; Simon E Barton; Mark Bower
Journal:  AIDS       Date:  2010-09-24       Impact factor: 4.177

2.  Anal cytology as a screening tool for anal squamous intraepithelial lesions.

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3.  Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups.

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Journal:  J Clin Oncol       Date:  1997-05       Impact factor: 44.544

4.  Achieving high coverage in Rwanda's national human papillomavirus vaccination programme.

Authors:  Agnes Binagwaho; Claire M Wagner; Maurice Gatera; Corine Karema; Cameron T Nutt; Fidele Ngabo
Journal:  Bull World Health Organ       Date:  2012-05-23       Impact factor: 9.408

5.  Human papillomavirus infection and cytologic abnormalities of the anus and cervix among HIV-infected women in the study to understand the natural history of HIV/AIDS in the era of effective therapy (the SUN study).

Authors:  Erna Milunka Kojic; Susan Cu-Uvin; Lois Conley; Tim Bush; Juanita Onyekwuluje; David C Swan; Elizabeth R Unger; Keith Henry; John H Hammer; Edgar T Overton; Teresa M Darragh; Joel M Palefsky; Claudia Vellozzi; Pragna Patel; John T Brooks
Journal:  Sex Transm Dis       Date:  2011-04       Impact factor: 2.830

6.  Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study.

Authors:  M Flam; M John; T F Pajak; N Petrelli; R Myerson; S Doggett; J Quivey; M Rotman; H Kerman; L Coia; K Murray
Journal:  J Clin Oncol       Date:  1996-09       Impact factor: 44.544

7.  Health systems and immunization financing for human papillomavirus vaccine introduction in low-resource settings.

Authors:  Robin Biellik; Carol Levin; Emmanuel Mugisha; D Scott LaMontagne; Allison Bingham; Satish Kaipilyawar; Sanjay Gandhi
Journal:  Vaccine       Date:  2009-08-19       Impact factor: 3.641

8.  Anorectal cytology as a screening tool for anal squamous lesions: cytologic, anoscopic, and histologic correlation.

Authors:  Maria A Friedlander; Elizabeth Stier; Oscar Lin
Journal:  Cancer       Date:  2004-02-25       Impact factor: 6.860

9.  The Anal Pap Smear: Cytomorphology of squamous intraepithelial lesions.

Authors:  Shehla Arain; Ann E Walts; Premi Thomas; Shikha Bose
Journal:  Cytojournal       Date:  2005-02-16       Impact factor: 2.091

10.  The feasibility of recruiting and retaining men who have sex with men and transgender women in a multinational prospective HIV prevention research cohort study in sub-Saharan Africa (HPTN 075).

Authors:  Theodorus Gm Sandfort; Erica L Hamilton; Anita Marais; Xu Guo; Jeremy Sugarman; Ying Q Chen; Vanessa Cummings; Sufia Dadabhai; Karen Dominguez; Ravindre Panchia; David Schnabel; Fatima Zulu; Doerieyah Reynolds; Oscar Radebe; Calvin Mbeda; Dunker Kamba; Brian Kanyemba; Arthur Ogendo; Michael Stirratt; Wairimu Chege; Jonathan Lucas; Maria Fawzy; Laura A McKinstry; Susan H Eshleman
Journal:  J Int AIDS Soc       Date:  2020-10       Impact factor: 5.396

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