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Literature DB >> 3610676

The morphogenesis of the human Paneth cell. An immunocytochemical ultrastructural study.

Abstract

In human duodenal mucosa Paneth cells originate away from the base of crypts and migrate towards the base during maturation. The earliest cells in the Paneth cell lineage could be identified by labelling of lysozyme in the Golgi apparatus. Specific labelling for lysozyme was present in the rough endoplasmic reticulum, Golgi apparatus, condensing vacuoles, granules and many lysosomes of mature Paneth cells. The maturation of the Paneth cell is accompanied by an increase in the content of lysozyme in the secretory granules and with senescence lysozyme diffuses into the cytoplasm.

Entities: Gene Species

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Year: 1987 PMID： 3610676 DOI： 10.1007/bf00518730

Source DB: PubMed Journal: Histochemistry ISSN： 0301-5564

15 in total

1. Paneth-cell function.

Authors: B Creamer
Journal: Lancet Date: 1967-02-11 Impact factor: 79.321

2. Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. IV. Paneth cells.

Authors: H Cheng
Journal: Am J Anat Date: 1974-12

3. Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell types.

Authors: H Cheng; C P Leblond
Journal: Am J Anat Date: 1974-12

4. Ultrastructural immunocytochemical localization of lysozyme in the Paneth cells of man.

Authors: S L Erlandsen; J A Parsons; T D Taylor
Journal: J Histochem Cytochem Date: 1974-06 Impact factor: 2.479

Review 5. Some recent developments in immunocytochemistry.

Authors: F T Bosman
Journal: Histochem J Date: 1983-03

6. Rectal mucosal morphologic abnormalities in normal subjects in southern India: a tropical colonopathy?

Authors: M M Mathan; V I Mathan
Journal: Gut Date: 1985-07 Impact factor: 23.059

7. Cytodifferentiation of the rat Paneth cell: an immunocytochemical investigation in suckling and weanling animals.

Authors: J Lopez-Lewellyn; S L Erlandsen
Journal: Am J Anat Date: 1980-07

8. Relation between the mucosal flora and Paneth cell population of human jejunum and ileum.

Authors: M E Elmes; M R Stanton; C H Howells; G H Lowe
Journal: J Clin Pathol Date: 1984-11 Impact factor: 3.411

9. Immunoglobulins within human small-intestinal Paneth cells.

Authors: C B Rodning; I D Wilson; S L Erlandsen
Journal: Lancet Date: 1976-05-08 Impact factor: 79.321

10. Immunocytochemical and histochemical studies on intestinal epithelial cells producing both lysozyme and mucosubstance.

Authors: C Montero; S L Erlandsen
Journal: Anat Rec Date: 1978-01

8 in total

The morphogenesis of the human Paneth cell. An immunocytochemical ultrastructural study.

1. Paneth-cell function.

2. Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. IV. Paneth cells.

3. Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell types.

4. Ultrastructural immunocytochemical localization of lysozyme in the Paneth cells of man.

Review 5. Some recent developments in immunocytochemistry.

6. Rectal mucosal morphologic abnormalities in normal subjects in southern India: a tropical colonopathy?

7. Cytodifferentiation of the rat Paneth cell: an immunocytochemical investigation in suckling and weanling animals.

8. Relation between the mucosal flora and Paneth cell population of human jejunum and ileum.

9. Immunoglobulins within human small-intestinal Paneth cells.

10. Immunocytochemical and histochemical studies on intestinal epithelial cells producing both lysozyme and mucosubstance.

1. Different epithelia in the distal human male urethra.

2. Expression of CD15 in normal and metaplastic Paneth cells of the digestive tract.

3. Enterochromaffin cells of the digestive system: cellular source of guanylin, a guanylate cyclase-activating peptide.

4. Degranulation of paneth cells via toll-like receptor 9.

5. Selective killing of Paneth cells by intravenous administration of dithizone in rats.

6. Atropine inhibits the degranulation of Paneth cells in ex-germ-free mice.

7. Colony stimulating factor-1 dependence of paneth cell development in the mouse small intestine.

8. Paneth cell metaplasia in newly diagnosed inflammatory bowel disease in children.