Adam Vegh1,2, Daniel Vegh3,4,5, Dorottya Banyai2,6, Gabor Kammerhofer2,7, Zita Biczo2,7, Balazs Voros2,7, Marta Ujpal1,2, Juan Francisco Peña-Cardelles2,8,9,10, Zehra Yonel2,11, Arpad Joob-Fancsaly1,2, Peter Hermann2,4, Zsolt Nemeth1,2. 1. Department of Oromaxillofacial Surgery and Stomatology, Semmelweis University, Budapest, Hungary. 2. Diabetes-Dental Working Group, Semmelweis University, Budapest, Hungary. 3. Diabetes-Dental Working Group, Semmelweis University, Budapest, Hungary; vegh.daniel.official@gmail.com vegh.daniel@dent.semmelweis-univ.hu. 4. Department of Prosthodontics, Semmelweis University, Budapest, Hungary. 5. Department of Dentistry and Oral Health, Division of Oral Surgery and Orthodontics, Medical University of Graz, Graz, Austria. 6. Department of Pedodontics and Orthodontics, Semmelweis University, Budapest, Hungary. 7. Faculty of Dentistry, Dental Student, Semmelweis University, Budapest, Hungary. 8. Department of Health Sciences, Rey Juan Carlos University, Madrid, Spain. 9. Oral and Maxillofacial Surgery Department, School of Dental Medicine, University of Connecticut Health, Farmington, CT, U.S.A. 10. Department of Prosthodontics, School of Dental Medicine, University of Connecticut Health, Farmington, CT, U.S.A. 11. Department of Restorative Dentistry, University of Birmingham, Birmingham, U.K.
Abstract
BACKGROUND/AIM: This study aimed to investigate the link between preoperative glycated hemoglobin (HbA1c) levels and oral cancer patients and diabetes mellitus (DM). We aimed to highlight the importance of point-of-care HbA1c measurements in oral cancer patients. PATIENTS AND METHODS: A total of 214 patients were admitted to the Department of Inpatient Care at Semmelweis University's Department of Oromaxillofacial Surgery and Stomatology between 1 September 2020 and 21 May 2021; individuals, who had undergone maxillofacial surgery under general anesthesia, were included in the study. RESULTS: There was a significant difference between the oral cancer group and the control group in terms of smoking (p=0.009) and alcohol intake (p=0.003). There was no statistically significant difference regarding sex (p=0.132) and DM (p=0.147) between the two groups. The tumor group had an 8.52% greater prevalence of DM, which was not significant. In the oral cancer group, twenty individuals (17.69%) had a higher HbA1c level than the upper level of the optimal metabolic value (6.9%). Nine participants (8.91%) in the control group had an HbA1c value greater than 6.9%, which means that their metabolic level was poor. The oral cancer group did not have higher blood glucose levels than those of the control group. CONCLUSION: No direct connection between high blood glucose levels and oral cancer was found. However, point-of-care HbA1c measurement can be a diagnostic tool to detect DM in the dental office.
BACKGROUND/AIM: This study aimed to investigate the link between preoperative glycated hemoglobin (HbA1c) levels and oral cancer patients and diabetes mellitus (DM). We aimed to highlight the importance of point-of-care HbA1c measurements in oral cancer patients. PATIENTS AND METHODS: A total of 214 patients were admitted to the Department of Inpatient Care at Semmelweis University's Department of Oromaxillofacial Surgery and Stomatology between 1 September 2020 and 21 May 2021; individuals, who had undergone maxillofacial surgery under general anesthesia, were included in the study. RESULTS: There was a significant difference between the oral cancer group and the control group in terms of smoking (p=0.009) and alcohol intake (p=0.003). There was no statistically significant difference regarding sex (p=0.132) and DM (p=0.147) between the two groups. The tumor group had an 8.52% greater prevalence of DM, which was not significant. In the oral cancer group, twenty individuals (17.69%) had a higher HbA1c level than the upper level of the optimal metabolic value (6.9%). Nine participants (8.91%) in the control group had an HbA1c value greater than 6.9%, which means that their metabolic level was poor. The oral cancer group did not have higher blood glucose levels than those of the control group. CONCLUSION: No direct connection between high blood glucose levels and oral cancer was found. However, point-of-care HbA1c measurement can be a diagnostic tool to detect DM in the dental office.
Authors: N H Cho; J E Shaw; S Karuranga; Y Huang; J D da Rocha Fernandes; A W Ohlrogge; B Malanda Journal: Diabetes Res Clin Pract Date: 2018-02-26 Impact factor: 5.602
Authors: Pablo Ramos-Garcia; Maria Del Mar Roca-Rodriguez; Manuel Aguilar-Diosdado; Miguel Angel Gonzalez-Moles Journal: Oral Dis Date: 2020-02-18 Impact factor: 3.511
Authors: Adam Vegh; Dorottya Banyai; Marta Ujpal; Kata Sara Somogyi; Zita Biczo; Gabor Kammerhofer; Zsolt Nemeth; Peter Hermann; Michael Payer; Daniel Vegh Journal: Anticancer Res Date: 2022-01 Impact factor: 2.480
Authors: Gábor Kammerhofer; Kata Sára Somogyi; Zita Biczó; Dániel Végh; Márta Ujpál; Mihály Tamás Vaszilkó; Dorottya Bányai; Attila Füzes; Ádám Végh; Árpád Joób-Fancsaly; Zsolt Németh Journal: Orv Hetil Date: 2022-04-10 Impact factor: 0.540
Authors: Terry C Simpson; Janet E Clarkson; Helen V Worthington; Laura MacDonald; Jo C Weldon; Ian Needleman; Zipporah Iheozor-Ejiofor; Sarah H Wild; Ambrina Qureshi; Andrew Walker; Veena A Patel; Dwayne Boyers; Joshua Twigg Journal: Cochrane Database Syst Rev Date: 2022-04-14