Literature DB >> 36096080

Laparoscopic resection for spontaneously ruptured primary extragastrointestinal stromal tumor of the greater omentum: A case report.

Takaaki Murata1, Takahiro Ishimori2, Wataru Naitou3, Yuto Igrashi2, Yuma Suno2, Jun Kawachi2.   

Abstract

INTRODUCTION: Ruptured extragastrointestinal stromal tumor (EGIST) are rare; therefore, there are no standard guidelines for its treatment. Herein, we report the successful laparoscopic resection of a ruptured EGIST. PRESENTATION OF CASE: The patient was a 59-year-old man, a Jehovah's Witness, who presented with sudden onset of left-sided abdominal pain. Contrast-enhanced computed tomography (CECT) performed from a previous hospital revealed intra-abdominal hemorrhage. Repeat CECT at our institution revealed extravasation and serum ascites. A hematoma was found anterior to the omentum, and a tumor was detected which did not have continuity with the surrounding organs of the gastrointestinal tract. Complete tumor resection via laparoscopic surgery was performed and the specimen was sent for histopathology, which revealed bundle-like proliferation of spindle-shaped cells. Immunohistochemical staining was completed, which was positive for KIT and CD34. Based on surgical and pathological findings, the final diagnosis was extragastrointestinal stromal tumor originating from the omentum. DISCUSSION: EGISTs have a similar morphology to that of gastrointestinal stromal tumors, but instead, arise outside the gastrointestinal tract. A significant differentiation and key to the diagnosis of EGIST is the absence of continuity with the gastrointestinal tract. The preferred treatment for EGIST is complete surgical resection, and the use of laparoscopy has not been well studied. Postoperative histopathological examination, along with immunohistochemical staining, aid confirmatory diagnosis.
CONCLUSION: Laparoscopic removal of EGISTs is a minimally invasive and potentially useful technique for the management of this tumor type.
Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  Case report; Extragastrointestinal stromal tumor; Gastrointestinal stromal tumor; Laparoscopy; Mesenchymal tumor

Year:  2022        PMID: 36096080      PMCID: PMC9568711          DOI: 10.1016/j.ijscr.2022.107567

Source DB:  PubMed          Journal:  Int J Surg Case Rep        ISSN: 2210-2612


  14 in total

1.  Primary omental gastrointestinal stromal tumour (GIST) presenting with a large abdominal mass and spontaneous haemoperitoneum.

Authors:  Isaac Seow-En; Francis Seow-Choen; Tony Kiat Hon Lim; Wei Qiang Leow
Journal:  BMJ Case Rep       Date:  2014-11-03

2.  Validation of the Joensuu risk criteria for primary resectable gastrointestinal stromal tumour - the impact of tumour rupture on patient outcomes.

Authors:  P Rutkowski; E Bylina; A Wozniak; Z I Nowecki; C Osuch; M Matlok; T Switaj; W Michej; M Wroński; S Głuszek; J Kroc; A Nasierowska-Guttmejer; H Joensuu
Journal:  Eur J Surg Oncol       Date:  2011-07-07       Impact factor: 4.424

3.  Gastrointestinal stromal tumors and KIT-positive mesenchymal cells in the omentum.

Authors:  S Sakurai; T Hishima; Y Takazawa; T Sano; T Nakajima; K Saito; S Morinaga; M Fukayama
Journal:  Pathol Int       Date:  2001-07       Impact factor: 2.534

Review 4.  Gastrointestinal stromal tumors: pathology and prognosis at different sites.

Authors:  Markku Miettinen; Jerzy Lasota
Journal:  Semin Diagn Pathol       Date:  2006-05       Impact factor: 3.464

5.  Gastrointestinal stromal tumors/smooth muscle tumors (GISTs) primary in the omentum and mesentery: clinicopathologic and immunohistochemical study of 26 cases.

Authors:  M Miettinen; J M Monihan; M Sarlomo-Rikala; A J Kovatich; N J Carr; T S Emory; L H Sobin
Journal:  Am J Surg Pathol       Date:  1999-09       Impact factor: 6.394

6.  Gastrointestinal stromal tumours: a regular origin in the muscularis propria, but an extremely diverse gross presentation. A review of 200 cases to critically re-evaluate the concept of so-called extra-gastrointestinal stromal tumours.

Authors:  Abbas Agaimy; Peter H Wünsch
Journal:  Langenbecks Arch Surg       Date:  2006-01-10       Impact factor: 3.445

Review 7.  Diagnosis of gastrointestinal stromal tumors: A consensus approach.

Authors:  Christopher D M Fletcher; Jules J Berman; Christopher Corless; Fred Gorstein; Jerzy Lasota; B Jack Longley; Markku Miettinen; Timothy J O'Leary; Helen Remotti; Brian P Rubin; Barry Shmookler; Leslie H Sobin; Sharon W Weiss
Journal:  Hum Pathol       Date:  2002-05       Impact factor: 3.466

8.  Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors.

Authors:  Seiichi Hirota; Akiko Ohashi; Toshirou Nishida; Koji Isozaki; Kazuo Kinoshita; Yasuhisa Shinomura; Yukihiko Kitamura
Journal:  Gastroenterology       Date:  2003-09       Impact factor: 22.682

9.  Risk stratification of patients diagnosed with gastrointestinal stromal tumor.

Authors:  Heikki Joensuu
Journal:  Hum Pathol       Date:  2008-10       Impact factor: 3.466

10.  Primary Extragastrointestinal Stromal Tumor of Greater Omentum with Intraperitoneal Bleeding: A Case Report.

Authors:  Masatoshi Kataoka; Tsukasa Saitoh; Kousaku Kawashima; Tomotaka Yazaki; Hiroki Sonoyama; Eiko Okimoto; Akihiko Oka; Yoshiyuki Mishima; Tsuyoshi Mishiro; Naoki Oshima; Kotaro Shibagaki; Hiroshi Tobita; Ichiro Moriyama; Norihisa Ishimura; Mamiko Nagase; Noriyuki Hirahara; Yoshitsugu Tajima; Shunji Ishihara
Journal:  Intern Med       Date:  2021-05-22       Impact factor: 1.271

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