Literature DB >> 3609328

Biotransformation of aromatic compounds. Monitoring fluorinated analogues by NMR.

A E Cass, D W Ribbons, J T Rossiter, S R Williams.   

Abstract

The results presented here illustrate the power of NMR in the non-invasive analysis of microbial transformations. Whilst the definitive identification of products requires purification and full structural elucidation. NMR can provide rapid insights into the nature of these reactions and their regulation in vivo. In addition, once the products have been identified NMR methods allow rapid assessment of the effects of genetic and physiological manipulation, and on competing metabolic fluxes with mixed substrates and branched pathways.

Mesh：

Substances：

Year:  1987        PMID： 3609328     DOI： 10.1016/0014-5793(87)80845-1

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  5 in total

1.  Isolation and initial characterization of a bacterial consortium able to mineralize fluorobenzene.

Authors:  M F Carvalho; C C T Alves; M I M Ferreira; P De Marco; P M L Castro
Journal:  Appl Environ Microbiol       Date:  2002-01       Impact factor: 4.792

2.  Enzymatic formation, stability, and spontaneous reactions of 4-fluoromuconolactone, a metabolite of the bacterial degradation of 4-fluorobenzoate.

Authors:  M Schlömann; P Fischer; E Schmidt; H J Knackmuss
Journal:  J Bacteriol       Date:  1990-09       Impact factor: 3.490

3.  19F nuclear magnetic resonance as a tool to investigate microbial degradation of fluorophenols to fluorocatechols and fluoromuconates.

Authors:  M G Boersma; T Y Dinarieva; W J Middelhoven; W J van Berkel; J Doran; J Vervoort; I M Rietjens
Journal:  Appl Environ Microbiol       Date:  1998-04       Impact factor: 4.792

4.  Purification and characterization of maleylacetate reductase from Alcaligenes eutrophus JMP134(pJP4).

Authors:  V Seibert; K Stadler-Fritzsche; M Schlömann
Journal:  J Bacteriol       Date:  1993-11       Impact factor: 3.490

5.  Conversion of 2-fluoromuconate to cis-dienelactone by purified enzymes of Rhodococcus opacus 1cp.

Authors:  Inna P Solyanikova; Olga V Moiseeva; Sjef Boeren; Marelle G Boersma; Marina P Kolomytseva; Jacques Vervoort; Ivonne M C M Rietjens; Ludmila A Golovleva; Willem J H van Berkel
Journal:  Appl Environ Microbiol       Date:  2003-09       Impact factor: 4.792
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.