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Literature DB >> 3609132

Intracerebroventricular neuropeptide Y protects against stress-induced gastric erosion in the rat.

Abstract

The effects of intracerebroventricular administration of neuropeptide Y (NPY) on stress-induced gastric erosion in the rat were investigated. Animals were exposed to water immersion stress after a single injection of 2 nmol NPY. Stress-induced erosion was reduced by approximately 50%. The plasma corticosterone levels were not affected. We interpret the protective effect of NPY as a manifestation of its sedative properties.

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Year: 1987 PMID： 3609132 DOI： 10.1016/0014-2999(87)90191-9

Source DB: PubMed Journal: Eur J Pharmacol ISSN： 0014-2999 Impact factor: 4.432

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Cited

12 in total

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Journal: J Physiol Biochem Date: 2000-09 Impact factor: 4.158

2. Salutary and prophylactic effect of pentadecapeptide BPC 157 on acute pancreatitis and concomitant gastroduodenal lesions in rats.

Authors: P Sikirić; S Seiwerth; Z Grabarević; R Rucman; M Petek; V Jagić; B Turković; I Rotkvić; S Mise; I Zoricić; L Jurina; P Konjevoda; M Hanzevacki; D Ljubanović; J Separović; M Gjurasin; M Bratulić; B Artuković; N Jelovac; G Buljat
Journal: Dig Dis Sci Date: 1996-07 Impact factor: 3.199

3. Pentadecapeptide BPC 157 interactions with adrenergic and dopaminergic systems in mucosal protection in stress.

Authors: P Sikirić; B Mazul; S Seiwerth; Z Grabarević; R Rucman; M Petek; V Jagić; B Turković; I Rotkvić; S Mise; I Zoricić; L Jurina; P Konjevoda; M Hanzevacki; M Gjurasin; J Separović; D Ljubanović; B Artuković; M Bratulić; M Tisljar; P Miklić; J Sumajstorcić
Journal: Dig Dis Sci Date: 1997-03 Impact factor: 3.199

4. Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety models.

Authors: M Heilig; B Söderpalm; J A Engel; E Widerlöv
Journal: Psychopharmacology (Berl) Date: 1989 Impact factor: 4.530

5. Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y overexpression.

Authors: A Thorsell; M Michalkiewicz; Y Dumont; R Quirion; L Caberlotto; R Rimondini; A A Mathé; M Heilig
Journal: Proc Natl Acad Sci U S A Date: 2000-11-07 Impact factor: 11.205

6. Beneficial effect of a novel pentadecapeptide BPC 157 on gastric lesions induced by restraint stress, ethanol, indomethacin, and capsaicin neurotoxicity.

Authors: P Sikirić; S Seiwerth; Z Grabarević; R Rucman; M Petek; V Jagić; B Turković; I Rotkvić; S Mise; I Zoricić; M Gjurasin; P Konjevoda; J Separović; D Ljubanović; B Artuković; M Bratulić; M Tisljar; L Jurina; G Buljat; P Miklić; A Marović
Journal: Dig Dis Sci Date: 1996-08 Impact factor: 3.199

7. Viral vector-induced amygdala NPY overexpression reverses increased alcohol intake caused by repeated deprivations in Wistar rats.

Authors: Annika Thorsell; Vez Repunte-Canonigo; Laura E O'Dell; Scott A Chen; Alvin R King; Dusan Lekic; George F Koob; Pietro Paolo Sanna
Journal: Brain Date: 2007-04-02 Impact factor: 13.501