Epitope-Specific T Cell Receptor Data and Tools in the Immune Epitope Database.

T cells play a critical role in the response of the immune system to non-self antigens. The Immune Epitope Database (IEDB) continuously curates published T cell data, among other immune-related data, and allows users to create custom queries based on their research interests and aims. The IEDB's companion site, the IEDB Analysis Resource, features a number of tools for analysis and prediction of immune epitopes; these include TCRMatch, a new tool used to predict candidate epitopes for T cell receptors with unknown specificity. Together these resources enable users to browse and filter large amounts of published data as well as generate hypotheses to guide future experiments.