Literature DB >> 36084071

Correction: MultipleTesting.com: A tool for life science researchers for multiple hypothesis testing correction.

Otília Menyhart, Boglárka Weltz, Balázs Győrffy.   

Abstract

[This corrects the article DOI: 10.1371/journal.pone.0245824.].

Entities:  

Year:  2022        PMID: 36084071      PMCID: PMC9462819          DOI: 10.1371/journal.pone.0274662

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.752


After the publication of this article [1] it was noticed that in the Sequential methods for multiple-testing correction subsection of the Introduction, the description of the Hochberg-correction contains an error. The correct paragraph is: The Hochberg-correction, also called the step-up method, is based on a reverse scenario when the largest p-value is examined first. Once a significant p-value is identified, all the remaining smaller p-values would be declared significant (13). For example, if n = 500, the largest p-values are 0.3, 0.05, 0.01, and α = 0.05, the following adjustments are concluded: Rank#1: 0.3 * 1 = 0.3, 0.3 > 0.05, the test is not significant Rank#2: 0.05 * 2 = 0.1, 0.1 > 0.05, the test is not significant Rank#3: 0.01 * 3 = 0.03, 0.03 < 0.05, the test is significant, reject the hull hypothesis, and all of the remaining p-values will be significant after correction. The authors have stated that the online tool developed for multiple hypothesis testing corrections at www.multipletesting.com employs the correct Hochberg step-up algorithm.
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1.  MultipleTesting.com: A tool for life science researchers for multiple hypothesis testing correction.

Authors:  Otília Menyhart; Boglárka Weltz; Balázs Győrffy
Journal:  PLoS One       Date:  2021-06-09       Impact factor: 3.752

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