Literature DB >> 3608208

Mucoepidermoid tumour of the parotid gland: a very difficult prognostic evaluation.

P Laudadio, U Caliceti, P T Cerasoli, A Rinaldi Ceroni.   

Abstract

The correct management of mucoepidermoid tumours is still debatable because of their unpredictable biological course. The issue discussed is that of identifying biological characteristics of these tumours which may have predictive value. Sixteen patients with a mucoepidermoid tumour of the parotid gland, treated at the ENT Clinic of Bologna University over a 15-year period, were reviewed. The follow-up of each patient has been related to the surgical management, in order to evaluate whether superficial parotidectomy provides adequate treatment. No prognostic differences were noted between total and superficial parotidectomy when the latter was clinically appropriate. The histopathological specimens from these patients were reviewed in an attempt to correlate the histological grade of tumour with the course of the disease. Our data suggest that histological evaluation of malignancy alone is insufficient for accurate prognosis. We think that the clinical presentation (facial nerve palsy, pain, etc.) predicts the prognosis with greater accuracy.

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Year:  1987        PMID: 3608208     DOI: 10.1111/j.1365-2273.1987.tb00184.x

Source DB:  PubMed          Journal:  Clin Otolaryngol Allied Sci        ISSN: 0307-7772


  4 in total

1.  Management of malignant parotid tumors.

Authors:  Nikolaos Papadogeorgakis; Lampros Goutzanis; Vassilis Petsinis; Constantinos Alexandridis
Journal:  Oral Maxillofac Surg       Date:  2011-01-05

2.  Prognostic significance of DNA ploidy in mucoepidermoid carcinoma.

Authors:  P Gemryd; P G Lundquist; M Tytor; H B Hellquist; B Nordenskjöld
Journal:  Eur Arch Otorhinolaryngol       Date:  1997       Impact factor: 2.503

3.  The relationship between nuclear DNA content in salivary gland tumors and prognosis. Comparison of mucoepidermoid tumors and acinic cell tumors.

Authors:  K Hamper; J Caselitz; H Arps; U Askensten; G Auer; G Seifert
Journal:  Arch Otorhinolaryngol       Date:  1989

4.  Mucoepidermoid carcinoma of the salivary glands, Clinical data and follow-up of 52 cases.

Authors:  K Plambeck; R E Friedrich; D Hellner; K Donath; R Schmelzle
Journal:  J Cancer Res Clin Oncol       Date:  1996       Impact factor: 4.553

  4 in total

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