| Literature DB >> 36078779 |
Wei He1, Nan Jin2, Huaxin Deng2, Qi Zhao2, Fang Yuan2, Fengqiong Chen2, Huadong Zhang2, Xiaoni Zhong1.
Abstract
OBJECTIVE: This study aims to determine the occupational health status of workers exposed to dust and the risk factors of lung function decline, to provide a basis for formulating corresponding occupational disease-prevention strategies.Entities:
Keywords: dust exposure; occupational health; pneumoconiosis; pulmonary function
Mesh:
Substances:
Year: 2022 PMID: 36078779 PMCID: PMC9518133 DOI: 10.3390/ijerph191711065
Source DB: PubMed Journal: Int J Environ Res Public Health ISSN: 1660-4601 Impact factor: 4.614
Figure 1Flowchart of the enrolled study subjects.
Factors related to pneumoconiosis-like changes.
| Characteristics | Total | Pneumoconiosis-like Changes | Chi-Square | |||
|---|---|---|---|---|---|---|
| N | % | No n (%) | Yes n (%) | |||
|
| 0.0539 | 0.8163 | ||||
| Normal | 899 | 43.96% | 892 (99.22%) | 7 (0.78%) | ||
| Abnormal | 1146 | 56.04% | 1136 (99.13%) | 10 (0.87%) | ||
|
| - |
| ||||
| Micro | 235 | 11.49% | 233 (99.15%) | 2 (0.85%) | ||
| Small | 1258 | 61.52% | 1243 (98.81%) | 15 (1.19%) | ||
| Medium | 552 | 26.99% | 552 (100.00%) | 0 (0.00%) | ||
|
| - |
| ||||
| Male | 1537 | 75.16% | 1520 (98.89%) | 17 (1.11%) | ||
| Female | 508 | 24.84% | 508 (100.00%) | 0 (0.00%) | ||
|
| 10.0673 |
| ||||
| ≤40 | 434 | 21.22% | 433 (99.77%) | 1 (0.23%) | ||
| 40–50 | 705 | 34.47% | 703 (99.72%) | 2 (0.28%) | ||
| >50 | 906 | 44.30% | 892 (98.45%) | 14 (1.55%) | ||
|
| 9.0236 |
| ||||
| ≤5 | 1011 | 49.44% | 1005 (99.41%) | 6 (0.59%) | ||
| 5–10 | 649 | 31.74% | 646 (99.54%) | 3 (0.46%) | ||
| >10 | 385 | 18.83% | 377 (97.92%) | 8 (2.08%) | ||
|
| - | 0.1804 a | ||||
| Coal dust | 8 | 0.39% | 8 (100.00%) | 0 (0.00%) | ||
| Limestone dust | 45 | 2.20% | 45 (100.00%) | 0 (0.00%) | ||
| Cement dust | 120 | 5.87% | 117 (97.50%) | 3 (2.50%) | ||
| Silica dust | 1872 | 91.54% | 1858 (99.25%) | 14 (0.75%) | ||
|
| 7.4922 |
| ||||
| <18.5 | 36 | 1.76% | 36 (100.00%) | 0 (0.00%) | ||
| 18.5–24.9 | 1269 | 62.05% | 1253 (98.74%) | 16 (1.26%) | ||
| ≥25 | 740 | 36.19% | 739 (99.86%) | 1 (0.14%) | ||
BMI: body mass index. a Fisher’s exact test method.
Factors related to abnormal lung function.
| Characteristics | Total | FEV1 | Chi-Square | FVC | Chi-Square | FEV1/FVC | Chi-Square | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | % | Normal | Abnormal | Normal | Abnormal | Normal | Abnormal | |||||||
|
| 4.1659 |
| 7.7046 |
| 5.2587 |
| ||||||||
| Normal | 899 | 43.96% | 870 (96.77%) | 29 (3.23%) | 763 (84.87%) | 136 (15.13%) | 892 (99.22%) | 7 (0.78%) | ||||||
| Abnormal | 1146 | 56.04% | 1088 (94.94%) | 58 (5.06%) | 1020 (89.01%) | 126 (10.99%) | 1123 (97.99%) | 23 (2.01%) | ||||||
|
| 33.162 |
| 70.1565 |
| 2.6056 | 0.2718 | ||||||||
| Micro | 235 | 11.49% | 228 (97.02%) | 7 (2.98%) | 191 (81.28%) | 44 (18.72%) | 234 (99.57%) | 1 (0.43%) | ||||||
| Small | 1258 | 61.52% | 1180 (93.80%) | 78 (6.20%) | 1055 (83.86%) | 203 (16.14%) | 1236 (98.25%) | 22 (1.75%) | ||||||
| Medium | 552 | 26.99% | 550 (99.64%) | 2 (0.36%) | 537 (97.28%) | 15 (2.72%) | 545 (98.73%) | 7 (1.27%) | ||||||
|
| 1.3675 | 0.2422 | 0.5667 | 0.4516 | 2.1596 | 0.1417 | ||||||||
| Male | 1537 | 75.16% | 1467 (95.45%) | 70 (4.55%) | 1345 (87.51%) | 192 (12.49%) | 1511 (98.31%) | 26 (1.69%) | ||||||
| Female | 508 | 24.84% | 491 (96.65%) | 17 (3.35%) | 438 (86.22%) | 70 (13.78%) | 504 (99.21%) | 4 (0.79%) | ||||||
|
| 17.4964 |
| 34.1521 |
| 10.3992 |
| ||||||||
| ≤40 | 434 | 21.22% | 430 (99.08%) | 4 (0.92%) | 408 (94.01%) | 26 (5.99%) | 431 (99.31%) | 3 (0.69%) | ||||||
| 40–50 | 705 | 34.47% | 675 (95.74%) | 30 (4.26%) | 624 (88.51%) | 81 (11.49%) | 700 (99.29%) | 5 (0.71%) | ||||||
| >50 | 906 | 44.30% | 853 (94.15%) | 53 (5.85%) | 751 (82.89%) | 155 (17.11%) | 884 (97.57%) | 22 (2.43%) | ||||||
|
| 0.4491 | 0.7989 | 4.2804 | 0.1176 | 1.5866 | 0.4523 | ||||||||
| ≤5 | 1011 | 49.44% | 967 (95.65%) | 44 (4.35%) | 867 (85.76%) | 144 (14.24%) | 995 (98.42%) | 16 (1.58%) | ||||||
| 5–10 | 649 | 31.74% | 624 (96.15%) | 25 (3.85%) | 579 (89.21%) | 70 (10.79%) | 638 (98.31%) | 11 (1.69%) | ||||||
| >10 | 385 | 18.83% | 367 (95.32%) | 18 (4.68%) | 337 (87.53%) | 48 (12.47%) | 382 (99.22%) | 3 (0.78%) | ||||||
|
| - |
| 18.6939 |
| - | 0.4812 a | ||||||||
| Coal dust | 8 | 0.39% | 8 (100.00%) | 0 (0.00%) | 8 (100.00%) | 0 (0.00%) | 8 (100.00%) | 0 (0.00%) | ||||||
| Limestone dust | 45 | 2.20% | 45 (100.00%) | 0 (0.00%) | 44 (97.78%) | 1 (2.22%) | 45 (100.00%) | 0 (0.00%) | ||||||
| Cement dust | 120 | 5.87% | 120 (100.00%) | 0 (0.00%) | 117 (97.50%) | 3 (2.50%) | 120 (100.00%) | 0 (0.00%) | ||||||
| Silica dust | 1872 | 91.54% | 1785 (95.35%) | 87 (4.65%) | 1614 (86.22%) | 258 (13.78%) | 1842 (98.40%) | 30 (1.60%) | ||||||
|
| 3.0123 | 0.2218 | 0.5834 | 0.7470 | 0.7088 | 0.7016 | ||||||||
| <18.5 | 36 | 1.76% | 35 (97.22%) | 1 (2.78%) | 31 (86.11%) | 5 (13.89%) | 36 (100.00%) | 0 (0.00%) | ||||||
| 18.5–24.9 | 1269 | 62.05% | 1222 (96.30%) | 47 (3.70%) | 1112 (87.63%) | 157 (12.37%) | 1249 (98.42%) | 20 (1.58%) | ||||||
| ≥25 | 740 | 36.19% | 701 (94.73%) | 39 (5.27%) | 640 (86.49%) | 100 (13.51%) | 730 (98.65%) | 10 (1.35%) | ||||||
FEV1: forced expiratory volume in one second; FVC: forced vital capacity. a Fisher’s exact test method.
Multivariate logistic regression analysis of pneumoconiosis-like changes and abnormal lung function.
| Dependent Variable | Model 1 (All Types of Dust) | Model 2 (Silica Dust) | ||||||
|---|---|---|---|---|---|---|---|---|
| Independent Variable | OR | 95%CI | Independent Variable | OR | 95%CI | |||
|
|
|
| ||||||
| ≤40 | Reference | ≤5 | Reference | |||||
| 40–50 | 1.046 | 0.094–11.637 | 0.3408 | 5–10 | 1.136 | 0.253–5.095 | 0.3385 | |
| >50 | 5.838 | 0.761–44.809 |
| >15 | 4.558 | 1.326–15.668 |
| |
|
| ||||||||
| ≤5 | Reference | |||||||
| 5–10 | 0.776 | 0.193–3.119 | 0.1825 | |||||
| >15 | 3.321 | 1.138–9.688 |
| |||||
|
|
|
| ||||||
| Micro | Reference | Micro | Reference | |||||
| Small | 2.246 | 1.020–4.942 |
| Small | 2.496 | 1.134–5.495 |
| |
| Medium | 0.151 | 0.031–0.737 |
| Medium | 0.161 | 0.033–0.787 |
| |
|
|
| |||||||
| ≤40 | Reference | ≤40 | Reference | |||||
| 40–50 | 3.951 | 1.376–11.344 | 0.0682 | 40–50 | 3.674 | 1.277–10.57 | 0.0848 | |
| >50 | 4.813 | 1.722–13.457 |
| >50 | 4.429 | 1.581–12.404 |
| |
|
|
|
| ||||||
| Normal | Reference | Normal | Reference | |||||
| Abnormal | 0.676 | 0.517–0.884 |
| Abnormal | 0.690 | 0.526–0.907 |
| |
|
|
| |||||||
| Micro | Reference | Micro | Reference | |||||
| Small | 0.932 | 0.646–1.345 |
| Small | 1.028 | 0.712–1.485 |
| |
| Medium | 0.157 | 0.084–0.291 |
| Medium | 0.158 | 0.084–0.297 |
| |
|
|
| |||||||
| ≤40 | Reference | ≤40 | Reference | |||||
| 40–50 | 1.767 | 1.107–2.819 | 0.4411 | 40–50 | 1.722 | 1.068–2.775 | 0.4313 | |
| >50 | 2.423 | 1.557–3.772 |
| >50 | 2.279 | 1.448–3.586 |
| |
|
|
|
| ||||||
| Normal | Reference | Normal | Reference | |||||
| Abnormal | 2.461 | 1.048–5.775 |
| Abnormal | 2.441 | 1.040–5.730 |
| |
|
|
| |||||||
| ≤40 | Reference | ≤40 | Reference | |||||
| 40–50 | 0.974 | 0.231–4.104 | 0.2508 | 40–50 | 0.939 | 0.223–3.955 | 0.2400 | |
| >50 | 3.323 | 0.987–11.189 |
| >50 | 3.175 | 0.943–10.694 |
| |