Literature DB >> 3607734

Clonal chromosome abnormalities in two liposarcomas.

F Mertens, B Johansson, N Mandahl, S Heim, K Bennet, A Rydholm, H Willén, F Mitelman.   

Abstract

Two liposarcomas were analyzed with chromosome banding technique. The sole chromosomal abnormality in one of the tumors, a mixed type (myxoid and round cell) liposarcoma, was t(12;16)(q13;p11), a rearrangement previously reported to be associated with myxoid liposarcoma. The other tumor, a pleomorphic liposarcoma, displayed massive numerical rearrangements (modal chromosome number 94-112), and numerous, mostly unidentifiable, marker chromosomes. The following clonal structural aberrations were recognized: del(1)(p22), del(1)(q23), t(7;?)(p22;?), i(17q), and t(19;?)(q13;?).

Entities:  

Mesh：

Year:  1987        PMID： 3607734     DOI： 10.1016/0165-4608(87)90363-3

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  8 in total

1.  In situ hybridization localizes the human putative oncogene GLI to chromosome subbands 12q13.3-14.1.

Authors:  K Arheden; M Rønne; N Mandahl; S Heim; K W Kinzler; B Vogelstein; F Mitelman
Journal:  Hum Genet       Date:  1989-04       Impact factor: 4.132

2.  Giant-cell tumor of bone, stage II, displaying translocation t(12;19)(q13;q13).

Authors:  R Noguera; A Llombart-Bosch; C Lopez-Gines; C Carda; C Fernandez
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1989

3.  Allelic deletions in the long arm of chromosome 12 identify sites of candidate tumor suppressor genes in male germ cell tumors.

Authors:  V V Murty; J Houldsworth; S Baldwin; V Reuter; W Hunziker; P Besmer; G Bosl; R S Chaganti
Journal:  Proc Natl Acad Sci U S A       Date:  1992-11-15       Impact factor: 11.205

4.  Bands involved in primary chromosome rearrangements in sarcomas are not constitutionally liable to breakage in sarcoma patients.

Authors:  F Mertens; B Johansson; S Heim; N Mandahl; A Rydholm; F Mitelman
Journal:  Hum Genet       Date:  1988-08       Impact factor: 4.132

5.  Three major cytogenetic subgroups can be identified among chromosomally abnormal solitary lipomas.

Authors:  N Mandahl; S Heim; K Arheden; A Rydholm; H Willén; F Mitelman
Journal:  Hum Genet       Date:  1988-07       Impact factor: 4.132

6.  FXR1, an autosomal homolog of the fragile X mental retardation gene.

Authors:  M C Siomi; H Siomi; W H Sauer; S Srinivasan; R L Nussbaum; G Dreyfuss
Journal:  EMBO J       Date:  1995-06-01       Impact factor: 11.598

7.  Amplification and Over-Expression of the MDM2 Gene in Human Soft Tissue Tumours.

Authors:  H Patterson; D Barnes; S Gill; J Spicer; C Fisher; M Thomas; R Grimer; C Fletcher; B Gusterson; C Cooper
Journal:  Sarcoma       Date:  1997

8.  Translocation t(12;16)(q13;p11) in myxoid liposarcoma of a child and implication of the human int-1 gene in tumorigenesis.

Authors:  Y Fujii; Y Matui; Y Nakagawa; T Hongo; Y Igarashi; M Yamada; Y Nakagome; S Tobayama
Journal:  Jpn J Cancer Res       Date:  1989-10
  8 in total

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