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Literature DB >> 360754

Immunodeficiency in hypophysectomized rats.

Abstract

The response of hypophysectomized, sham-operated and non-operated female Fischer 344 and Wistar-Furth rats was compared to various antigenic stimuli. Antibody production against sheep red blood cells, skin response to dinitrochlorobenzene and the development of adjuvant arthritis after treatment with Freund's complete adjuvant were all markedly suppressed in hypophysectomized animals. Sham-operated rats responded as well as did non-operated controls. Skin graft survival was also prolonged in hypophysectomized rats when compared to controls. These results indicate that the pituitary gland plays an important role in immune reactions.

Entities: Chemical Disease Species

Mesh：

Substances：
Dinitrochlorobenzene

Year: 1978 PMID： 360754 DOI： 10.1530/acta.0.0890530

Source DB: PubMed Journal: Acta Endocrinol (Copenh) ISSN： 0001-5598

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Cited

22 in total

Review 1. Interleukins and neurohormones: a common language.

Authors: R Knight; N Sarlis; A Stephanou
Journal: Postgrad Med J Date: 1992-08 Impact factor: 2.401

2. Age-related capacity of neuroendocrine factors to differentiate T cells in vitro.

Authors: P Esquivel; C Rivas; M Mena; M Barria; H Folch
Journal: Immunology Date: 1992-01 Impact factor: 7.397

Review 3. Growth hormone. A paracrine growth factor?

Authors: S Harvey; K L Hull
Journal: Endocrine Date: 1997-12 Impact factor: 3.633

Review 4. The role of prolactin in the pathogenesis of autoimmune disease.

Authors: Istvan Berczi
Journal: Endocr Pathol Date: 1993-12 Impact factor: 3.943

5. Dynamics of spermatogenesis, hormonal and immune response of patients suffering from chronic prostatitis and sterility under bitemporal treatment with an ultra-high frequency electric field.

Authors: V M Bogolyubov; I V Karpukhin; A S Bobkova; A V Razuvayev; E V Kozhinova
Journal: Int Urol Nephrol Date: 1986 Impact factor: 2.370

10. Hyperprolactinemia inhibits natural killer (NK) cell function in vivo and its bromocriptine treatment not only corrects it but makes it more efficient.

Authors: A Vidaller; F Guadarrama; L Llorente; J B Méndez; F Larrea; A R Villa; D Alarcón-Segovia
Journal: J Clin Immunol Date: 1992-05 Impact factor: 8.317

Immunodeficiency in hypophysectomized rats.

Review 1. Interleukins and neurohormones: a common language.

2. Age-related capacity of neuroendocrine factors to differentiate T cells in vitro.

Review 3. Growth hormone. A paracrine growth factor?

Review 4. The role of prolactin in the pathogenesis of autoimmune disease.

5. Dynamics of spermatogenesis, hormonal and immune response of patients suffering from chronic prostatitis and sterility under bitemporal treatment with an ultra-high frequency electric field.

6. Treatment of paroxysmal symptoms in multiple sclerosis with bromocriptine.

7. Immunosuppressive property of bromocriptine on human B lymphocyte function in vitro.

8. Growth hormone alters lymphocyte sub-populations and antibody production in dwarf rats in vivo.

9. Rapid activation of protein kinase C in isolated rat liver nuclei by prolactin, a known hepatic mitogen.

10. Hyperprolactinemia inhibits natural killer (NK) cell function in vivo and its bromocriptine treatment not only corrects it but makes it more efficient.