| Literature DB >> 3607474 |
W H Church, J B Justice, D B Neill.
Abstract
A method is described for monitoring extracellular levels of striatal dopamine in the rat during behavior. The extracellular fluid is sampled using a microdialysis probe modified for use in behaving animals. Dopamine concentration in the perfusate is determined every 5 min using an automated smallbore chromatographic system with electrochemical detection. The system is capable of detecting behaviorally related changes of 5 nM, in extracellular dopamine.Entities:
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Year: 1987 PMID： 3607474 DOI： 10.1016/0006-8993(87)91150-4
Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252